The Kalochori Accelerometric Network (KAN) has been operating since 2014 in the urban area of Kalochori, 7 km west of Thessaloniki in Northern Greece. KAN is composed of seven accelerometric stations: three ground stations installed in distinct urban zones (i.e., residential, industrial, and tanks zone); three stations on top of a selected structure within each urban zone; and one free-field station away from the built environment. The stations are documented with installation and operating features, available characteristics of the housing structures, and geotechnical data. A set of 78 earthquakes that have been recorded by KAN between 16 January 2014 and 31 December 2016 are reported, allowing investigation of local site effects on seismic motion, variation of ground surface motion within different urban environments, and evaluation of dynamic response features of the instrumented structures. KAN stations monographs, processed acceleration recordings, and metadata of the recorded earthquakes are available online through a Web-GIS platform. Indicative example applications are discussed for possible data use in the field of soil and structural dynamics. The DOI linked to the complete set of KAN data is 10.6084/m9.figshare.5044804.