Monitoring of Serum α-Fetoprotein Levels in Children with Chronic Hepatitis B Virus Infection

Vajro, Pietro; Fontanella, Angiola; Vincenzo, Anna De; Lettera, P.; Greco, Luigi; Coppa, Anna; D'Armiento, M.

doi:10.1097/00005176-199101000-00006

Cited by 3 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…5 Patients with chronic hepatitis B and elevated serum AFP levels have more regenerative changes than patients without elevated serum AFP values. 44 When the hepatocyte plates of the adult liver are damaged, the hepatocytes change shape, become "isolated" from the ends of the plates, and express AFP. 42 Hepatocytes that become architecturally arranged into normal adult-type plates cease to produce AFP.…”

Section: Hepatitis C and Ssrum Cc-fetoproteinmentioning

confidence: 99%

Serum α-Fetoprotein Levels in Patients with Chronic Hepatitis C : Relationships With Serum Alanine Aminotransferase Values, Histologic Activity Index, and Hepatocyte MIB-1 Scores

et al. 1999

View full text Add to dashboard Cite

Patients with chronic viral hepatitis and cirrhosis often have elevated serum (X-fetoprotein (AFP) values, the causes of which are unclear. We studied 81 patients with chronic hepatitis C and the relationships of serum AFP and alanine aminotransferase (ALT) values Materials and MethodsTwo hundred consecutively evaluated patients with chronic hepatitis C who underwent liver needle biopsy at the time of initial examination and whose serum AFP levels were measured at the time of biopsy were identified by the William

show abstract

Section: Hepatitis C and Ssrum Cc-fetoproteinmentioning

confidence: 99%

Serum α-Fetoprotein Levels in Patients with Chronic Hepatitis C : Relationships With Serum Alanine Aminotransferase Values, Histologic Activity Index, and Hepatocyte MIB-1 Scores

et al. 1999

View full text Add to dashboard Cite

show abstract

Laboratory assessment of hepatobiliary disease

Mowat

1994

Liver Disorders in Childhood

View full text Add to dashboard Cite

An update on the strategies used for the treatment of chronic hepatitis B in children

Clemente

Vajro²

2016

Expert Review of Gastroenterology & Hepatology

View full text Add to dashboard Cite

Chronic hepatitis B (CHB) in children shows a variety of clinical presentations, which influence its natural course and treatment options. This report provides an overview of the ongoing strategies in pediatric CHB management. Interferon-α represents the first choice of treatment in children showing HBV replication and hepatic inflammation (immune active CHB), while the recommendation is to monitor inactive/immune-tolerant children (normal transaminases and low/absent viral replication). When circumstances preclude the use of Interferon-α and in cases of compensated/decompensated cirrhosis, entecavir for children above 2 years of age or tenofovir for children above 12 years of age are the nucleos(t)ide analogues recommended by the most recent guidelines.

show abstract

Monitoring of Serum α-Fetoprotein Levels in Children with Chronic Hepatitis B Virus Infection

Cited by 3 publications

References 0 publications

Serum α-Fetoprotein Levels in Patients with Chronic Hepatitis C : Relationships With Serum Alanine Aminotransferase Values, Histologic Activity Index, and Hepatocyte MIB-1 Scores

Serum α-Fetoprotein Levels in Patients with Chronic Hepatitis C : Relationships With Serum Alanine Aminotransferase Values, Histologic Activity Index, and Hepatocyte MIB-1 Scores

Laboratory assessment of hepatobiliary disease

An update on the strategies used for the treatment of chronic hepatitis B in children

Contact Info

Product

Resources

About