Monitoring of Phenolic Compounds for the Quality Control of <i>Melissa officinalis</i> Products by Capillary Electrophoresis

Acosta, Gimena; Arce, Silvia; Martínez, Luis D.; Llabot, Juan Manuel; Gómez, María R.

doi:10.1002/pca.1340

Cited by 15 publications

(7 citation statements)

References 22 publications

(22 reference statements)

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“…However, capillary zone electrophoresis (CZE) and micellar electrokinetic chromatography (MEKC) are the main two used for RA quantitation. In the CZE experiments, a sodium borate solution was used as the run buffer to determine the RA in Salvia officinalis tea samples [ 218 ], in 14 Salvia species [ 219 ], in Origanum Vulgare L. [ 220 ], and in Melissa officinalis products [ 221 ]. In the MEKC studies, to obtain a satisfactory separation of RA from the other components, some additives were supplemented to the buffer such as β-cyclodextrin [ 222 , 223 ] and sodium dodecylsulfate [ 224 ].…”

Section: Analytical Techniquementioning

confidence: 99%

A Comprehensive Review of Rosmarinic Acid: From Phytochemistry to Pharmacology and Its New Insight

et al. 2022

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Polyphenolic acids are the widely occurring natural products in almost each herbal plant, among which rosmarinic acid (RA, C18H16O8) is well-known, and is present in over 160 species belonging to many families, especially the Lamiaceae. Aside from this herbal ingredient, dozens of its natural derivatives have also been isolated and characterized from many natural plants. In recent years, with the increasing focus on the natural products as alternative treatments, a large number of pharmacological studies have been carried out to demonstrate the various biological activities of RA such as anti-inflammation, anti-oxidation, anti-diabetes, anti-virus, anti-tumor, neuroprotection, hepatoprotection, etc. In addition, investigations concerning its biosynthesis, extraction, analysis, clinical applications, and pharmacokinetics have also been performed. Although many achievements have been made in various research aspects, there still exist some problems or issues to be answered, especially its toxicity and bioavailability. Thus, we hope that in the case of natural products, the present review can not only provide a comprehensive understanding on RA covering its miscellaneous research fields, but also highlight some of the present issues and future perspectives worth investigating later, in order to help us utilize this polyphenolic acid more efficiently, widely, and safely.

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Section: Analytical Techniquementioning

confidence: 99%

A Comprehensive Review of Rosmarinic Acid: From Phytochemistry to Pharmacology and Its New Insight

et al. 2022

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“…Ценное эфирное масло мелиссы фальсифицируют дешевым маслом цитронеллы (мелиссы лимонной) [73]. Эфирное масло розы может быть фальсифицировано более дешевыми маслами, содержащими терпеновые спирты (цитронеллол, гераниол), фракциями гераниевого масла или пальмарозовым [74].…”

Section: способы фальсификации эфирных маселunclassified

Essential oils: the review of the methods for determining the authenticity and detecting adulteration

Aksenova¹,

Kuznecova²,

Vasilevskij³

et al. 2019

АиК

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Эфирные масла являются продуктами природного происхождения, которые находят самое разнообразное применение в различных областях промышленности. Высокая стоимость, трудоемкость производства и широкое использование приводят к тому, что в продаже наряду с качественными эфирными маслами часто встречают фальсифицированные. Применение поддельных масел повышает их опасность для человека, в связи с чем установление подлинности эфирных масел имеет большое значение. В обзоре проведен анализ опубликованных работ и нормативных документов, посвященных вопросам определения подлинности и выявления фальсификации эфирных масел. Рассмотрен компонентный состав эфирных масел, его вариабельность в зависимости от места произрастания эфиромасличного растения и технологии выделения масла. Обсуждены основные способы фальсификации эфирных масел и спектр используемых для этого приемов, необходимость применения соответствующих методов исследования, позволяющих контролировать подлинность продукции. Проведен анализ литературы и нормативной базы, регламентирующей качество эфирных масел, существующих методов определения их подлинности, указывают достоинства и недостатки. Особое внимание уделено методу масс-спектрометрии изотопных отношений, как наиболее перспективному, вследствие высокой точности и возможности применения для исследования практически любого типа масла. Приведены основные теоретические положения исследования стабильных изотопов и их фракционирования, принципиальные особенности методов измерения. Подтверждено широкое использование метода масс-спектрометрии изотопных отношений на практике конкретными примерами с демонстрацией новых возможностей данного метода, связанных с использованием изотопного профилирования и комбинированных методов изотопного анализа. Отмечена важность для определения подлинности масел информации об изотопном составе их компонентов, который является индикатором любых искусственных процессов, происходящих с эфирным маслом в результате фальсификации.

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“…Principal component analysis was used to show differences of constituents that were found dependent on the bee strain type. A CZE method was developed for the analysis of phenolic compounds of Melissa officinalis L. . The investigated samples of commercial M. officinalis L. in a survey carried out in different herbal shops in Argentina corresponded to the bioactivity of Nepeta cataria .…”

Section: Applicationsmentioning

confidence: 99%

Capillary electrophoresis of natural products: 2011–2012

et al. 2014

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Bioactive natural products are major sources of lead compounds for drug discovery and pharmaceutical development, therefore, innovative and current separation and characterization techniques are important for these compounds. Here, CE methods applied for the analysis of natural products published during 2011-2012 are reviewed. This is an updated version of an earlier review paper in this journal, which highlighted developments during 2006-2010. The major method developments over the review period centered on derivatization, chiral analysis, modes of detection, stacking or on-line sample concentration, and sample preparation (predominantly using extraction methods). The samples analyzed were herbal products, foods, soil, and biological samples. Developments also occurred in the areas of quality control, toxicology assessment, and enzyme-inhibitor screening. A table that summarizes the areas, source of natural product, nature of the bioactive analyte, CE conditions, LODs, and corresponding reference is provided. A short description on the theory of CE and insights on future activities of CE on natural products are also presented.

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Monitoring of Phenolic Compounds for the Quality Control of Melissa officinalis Products by Capillary Electrophoresis

Abstract: The proposed methodology can be applied to the standardisation and quality control of plant material and phytopharmaceutical products derived from the Lamiaceae family, as indicated by the results obtained in the analysis of commercial medicinal products in Argentina.

Cited by 15 publications

References 22 publications

A Comprehensive Review of Rosmarinic Acid: From Phytochemistry to Pharmacology and Its New Insight

A Comprehensive Review of Rosmarinic Acid: From Phytochemistry to Pharmacology and Its New Insight

Essential oils: the review of the methods for determining the authenticity and detecting adulteration

Capillary electrophoresis of natural products: 2011–2012

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