Monitoring of paediatric type 1 diabetes

Marks, Brynn E.; Wolfsdorf, Joseph I.

doi:10.1097/mop.0000000000001136

Cited by 3 publications

(1 citation statement)

References 65 publications

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“…Stable glycemic control can be achieved via a balance between pharmacological approach and nutrition [ 63 , 64 ]. However, despite medical advances, only 20% of children with T1D succeeds in reaching a target of HbA1c <7.5% [ 65 , 66 ]. Much interest has been given to diets characterized by a reduced carbohydrate intake, because it has been observed that lower carbohydrate consumption is associated with a greater glycemic stability [ 67 ].…”

Section: Studies Focusing On Diets Characterized By Different Quantit...mentioning

confidence: 99%

Diet and Glycemic Index in Children with Type 1 Diabetes

et al. 2023

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In children with type 1 diabetes, a healthy lifestyle is important to control postprandial glycemia and to avoid hyperglycemic peaks that worsen the inflammatory state of vessels and tissues. Glycemic index and glycemic load are two important indexes which assess the quality and quantity of foods consumed during meals. The main macronutrients of the diet have a different effect on postprandial blood glucose levels, so it is important that diabetic children consume foods which determine a slower and steadier glycemic peak. In this review, we present the results of the most recent studies carried out in the pediatric population with T1D, whose aim was to analyze the effects of low-glycemic-index foods on glycemic control. The results are promising and demonstrate that diets promoting low-glycemic-index foods guarantee a greater glycemic stability with a reduction in postprandial hyperglycemic peaks. However, one of the main limitations is represented by the poor adherence of children to a healthy diet. In order to obtain satisfactory results, a possibility might be to ensure a balanced intake of low-, moderate- and high-glycemic-index foods, preferring those with a low glycemic index and limiting the consumption of the high- and moderate-glycemic-index types.

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Section: Studies Focusing On Diets Characterized By Different Quantit...mentioning

confidence: 99%

Diet and Glycemic Index in Children with Type 1 Diabetes

et al. 2023

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Mesenchymal Stem Cell Transplantation in Type 1 Diabetes Treatment: Current Advances and Future Opportunity

Liu,

Wan,

Zheng

et al. 2024

CSCR

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Type 1 Diabetes (T1D) is characterized by hyperglycemia, and caused by a lack of insulin secretion. At present there is no cure for T1D and patients are dependent on exogenous insulin for lifelong, which seriously affects their lives. Mesenchymal stem cells (MSCs) can be differentiated to β cell-like cells to rescue the secretion of insulin and reconstruct immunotolerance to preserve the function of islet β cells. Due to the higher proportion of children and adolescents in T1D patients, the efficacy and safety issue of the application of MSC’s transplant in T1D was primarily demonstrated and identified by human clinical trials in this review. Then we clarified the mechanism of MSCs to relieve the symptom of T1D and found out that UC-MSCs have no obvious advantage over the other types of MSCs, the autologous MSCs from BM or menstrual blood with less expanded ex vivo could be the better choice for clinical application to treat with T1D through documentary analysis. Finally, we summarized the advances of MSCs with different interventions such as genetic engineering in the treatment of T1D, and demonstrated the advantages and shortage of MSCs intervened by different treatments in the transplantation, which may enhance the clinical efficacy and overcome the shortcomings in the application of MSCs to T1D in future.

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Experiences With Outpatient Nutrition Services Among Caregivers of Youth With Type 1 Diabetes

Gordon,

Dykeman,

Greco

et al. 2024

Diabetes Spectrum

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Many children with type 1 diabetes do not meet nutritional guidelines. Little is known about how caregivers perceive the necessity of registered dietitian (RD) visits or how satisfied they are with nutrition care. This study aimed to evaluate nutrition experiences and perceptions of care among caregivers of children with type 1 diabetes at an academic medical center. We analyzed 159 survey responses. Using multivariable logistic regression, we assessed factors associated with the perception of need for annual nutrition visits, satisfaction with RD care, and encouragement from a nurse or doctor to meet with an RD. Covariates included age (<13 vs. ≥13 years), type 1 diabetes duration (≤3 vs. >3 years), sex, race/ethnicity, and insulin pump and continuous glucose monitoring use. More than half of caregivers (56%) considered annual visits necessary. Shorter type 1 diabetes duration (odds ratio [OR] 1.92, 95% CI 1.02–3.63) was associated with this finding. Less than half (46.5%) reported satisfaction with nutrition care; higher satisfaction was also correlated with shorter type 1 diabetes duration (OR 2.20, 95% CI 1.17–4.15). Although 42% reported meeting with an RD in the past year, less than two-thirds (62%) reported receiving a medical provider recommendation for nutrition care. Leading reasons for not meeting with an RD were: “I am knowledgeable in nutrition and do not need to see an [RD]” (41%) and “I had a past visit with an [RD] that was not helpful” (40%). Our findings suggest that satisfaction with and perceived need for nutrition care may wane with longer type 1 diabetes duration. Improved strategies for therapeutic alliance between caregivers and RDs and engagement of families at later stages of type 1 diabetes are needed.

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Monitoring of paediatric type 1 diabetes

Cited by 3 publications

References 65 publications

Diet and Glycemic Index in Children with Type 1 Diabetes

Diet and Glycemic Index in Children with Type 1 Diabetes

Mesenchymal Stem Cell Transplantation in Type 1 Diabetes Treatment: Current Advances and Future Opportunity

Experiences With Outpatient Nutrition Services Among Caregivers of Youth With Type 1 Diabetes

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