Monitoring of hepatitis E virus in wastewater can identify clinically relevant variants
Fiona Rau,
Carina Elsner,
Toni Luise Meister
et al.
Abstract:Hepatitis E virus (HEV) is prevalent worldwide and can cause persistent infection with severe morbidity. Antiviral treatment approaches can lead to the emergence of viral variants encoding escape mutations that may impede viral clearance. The frequency of these variants remains unknown in the human population as well as environment due to limited comprehensive data on HEV diversity. In this study, we investigated the HEV prevalence and diversity of circulating variants in environmental samples, that is, wastew… Show more
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