Monitoring Neuromuscular Blockade

Brull, Sorin J.; Silverman, David G.; Naguib, Mohamed

doi:10.1016/b978-0-323-11237-6.00015-7

Cited by 4 publications

(14 citation statements)

References 123 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…It is not known whether the duration of stabilization influences the skin-electrode interface during recording, but skin curing time necessary for effective nerve depolarization via the gel electrodes may require 10-15 min. 42 Both inspection of the EMG signal and the criteria for an acceptable response are important. Ideally, the EMG response should have a two-phase profile with a well-defined initial upward (negative) deflection not influenced by stimulation artifacts.…”

Section: Electromyographymentioning

confidence: 99%

See 1 more Smart Citation

Good clinical research practice (GCRP) in pharmacodynamic studies of neuromuscular blocking agents III: The 2023 Geneva revision

Fuchs‐Buder

Brull

Fagerlund

et al. 2023

Acta Anaesthesiol Scand

View full text Add to dashboard Cite

The set of guidelines for good clinical research practice in pharmacodynamic studies of neuromuscular blocking agents was developed following an international consensus conference in Copenhagen in 1996 (Viby‐Mogensen et al., Acta Anaesthesiol Scand 1996, 40, 59–74); the guidelines were later revised and updated following the second consensus conference in Stockholm in 2005 (Fuchs‐Buder et al., Acta Anaesthesiol Scand 2007, 51, 789–808). In view of new devices and further development of monitoring technologies that emerged since then, (e.g., electromyography, three‐dimensional acceleromyography, kinemyography) as well as novel compounds (e.g., sugammadex) a review and update of these recommendations became necessary. The intent of these revised guidelines is to continue to help clinical researchers to conduct high‐quality work and advance the field by enhancing the standards, consistency, and comparability of clinical studies.There is growing awareness of the importance of consensus‐based reporting standards in clinical trials and observational studies. Such global initiatives are necessary in order to minimize heterogeneous and inadequate data reporting and to improve clarity and comparability between different studies and study cohorts. Variations in definitions of endpoints or outcome variables can introduce confusion and difficulties in interpretation of data, but more importantly, it may preclude building of an adequate body of evidence to achieve reliable conclusions and recommendations. Clinical research in neuromuscular pharmacology and physiology is no exception.

show abstract

Section: Electromyographymentioning

confidence: 99%

“…Ag/AgCl electrodes with a recording diameter of 0.7–1.1 cm are normally used. It is not known whether the duration of stabilization influences the skin‐electrode interface during recording, but skin curing time necessary for effective nerve depolarization via the gel electrodes may require 10–15 min 42 …”

Section: Reporting Guidelines For Studies On Nmbasmentioning

confidence: 99%

Good clinical research practice (GCRP) in pharmacodynamic studies of neuromuscular blocking agents III: The 2023 Geneva revision

Fuchs‐Buder

Brull

Fagerlund

et al. 2023

Acta Anaesthesiol Scand

View full text Add to dashboard Cite

show abstract

“…Den nevromuskulaere blokaden må vaere reversert før pasienten skal vekkes fra gene rell anestesi. Muskelrelakserende legemidler har ulik virkningsmekanisme og eliminasjon, derfor vil tidspunkt for muskelgjenvinning og egnet tidspunkt for ekstubasjon variere (2,3).…”

Section: Innledningunclassified

“…I litteraturen er det god dokumentasjon på at kliniske tegn og vurderinger ikke er tilstrekkelig for å vurdere om en nevromuskulaer blokade er tilfredsstillende opphevet. De kliniske tegnene viser at muskelkraften er tilbake, og at den nevromuskulaere blokaden ikke er dyp (2,3,6).…”

Section: Innledningunclassified

See 1 more Smart Citation

Monitorering og reversering av nevromuskulær blokade – en kunnskapsbasert prosedyre

Aarsnes¹,

Reine²

2023

inspira

View full text Add to dashboard Cite

Bakgrunn: Muskelrelakserende legemidler brukes for å legge til rette for endotrakeal intubasjon og kirurgi. Legemidlene gir en nevromuskulær blokade av skjelettmuskulatur som må være reversert før pasienten ekstuberes. Pasienter som fortsatt er påvirket av nevromuskulær blokade etter generell anestesi er restkurarisert. Dette er ubehagelig for pasienten og kan medføre ulike komplikasjoner. På bakgrunn av ulik praksis knyttet til monitorering og reversering av nevromuskulær blokade ønsket vi å utarbeide en kunnskapsbasert fagprosedyre som beslutningsstøtte til sykepleiere og leger i anestesiavdelingen. Hensikt: Formålet var å utarbeide en kunnskapsbasert fagprosedyre for monitorering og reversering av nevromuskulær blokade. Metode: Kunnskapssenterets modell for kvalitetsforbedring og Helsedirektoratets «Veileder for utvikling av kunnskapsbaserte retningslinjer» (2012) ble brukt som metode. Kvalitetsvurdering av fagprosedyren ble gjennomført med AGREE II. Kunnskapsgrunnlaget for anbefalingene er basert på en systematisk gjennomgang av forskningslitteratur og kritisk vurdering av denne, samt erfaringskunnskap. Resultat: Litteratursøkene identifiserte over 600 studier, hvorav syv artikler ble inkludert i kunnskapsgrunnlaget for prosedyren. Forskningslitteraturen viser at kliniske tegn og vurderinger ikke er tilstrekkelig for å avdekke om en nevromuskulær blokade er adekvat opphevet. Nevromuskulær monitorering er en sikrere metode som bør brukes når muskelrelakserende legemidler administreres til pasienter i generell anestesi. Konklusjon: En kunnskapsbasert prosedyre kan bidra til mer kunnskapsbasert praksis i monitorering og reversering av muskelrelakserende legemidler. Dette kan bidra til å forebygge restkurarisering og bedre kvaliteten og sikkerheten i pasientbehandlingen peroperativt.

show abstract

Surface Electromyography in Dentistry—Past, Present and Future

Zieliński,

Gawda

2024

JCM

View full text Add to dashboard Cite

Surface electromyography (sEMG) is a technique for measuring and analyzing the electrical signals of muscle activity using electrodes placed on the skin’s surface. The aim of this paper was to outline the history of the development and use of surface electromyography in dentistry, to show where research and technical solutions relating to surface electromyography currently lie, and to make recommendations for further research. sEMG is a diagnostic technique that has found significant application in dentistry. The historical section discusses the evolution of sEMG methods and equipment, highlighting how technological advances have influenced the accuracy and applicability of this method in dentistry. The need for standardization of musculoskeletal testing methodology is highlighted and the needed increased technical capabilities of sEMG equipment and the ability to specify parameters (e.g., sampling rates, bandwidth). A higher sampling rate (the recommended may be 2000 Hz or higher in masticatory muscles) allows more accurate recording of changes in the signal, which is essential for accurate analysis of muscle function. Bandwidth is one of the key parameters in sEMG research. Bandwidth determines the range of frequencies effectively recorded by the sEMG system (the recommended frequency limits are usually between 20 Hz and 500 Hz in masticatory muscles). In addition, the increased technical capabilities of sEMG equipment and the ability to specify electromyographic parameters demonstrate the need for a detailed description of selected parameters in the methodological section. This is necessary to maintain the reproducibility of sEMG testing. More high-quality clinical trials are needed in the future.

show abstract

Monitoring Neuromuscular Blockade

Cited by 4 publications

References 123 publications

Good clinical research practice (GCRP) in pharmacodynamic studies of neuromuscular blocking agents III: The 2023 Geneva revision

Good clinical research practice (GCRP) in pharmacodynamic studies of neuromuscular blocking agents III: The 2023 Geneva revision

Monitorering og reversering av nevromuskulær blokade – en kunnskapsbasert prosedyre

Surface Electromyography in Dentistry—Past, Present and Future

Contact Info

Product

Resources

About