We are in the Big Data era, characterized by an increasing amount of information generated everyday by all the phenomena concerning our life. These data are collected by many information sources and systems ranging from IoT sensors, large databases, social networks and interactive platforms, as well as generic media like images, videos and audios. Thus, to be able to comprehend the phenomena underlying this data there is the need of designing effective visualization tools. The papers selected for this special issue outline and evaluate some recent works on multimedia tools for information visualization and interaction with various types of data, including textual documents, graphs, spatio-temporal data, multimedia contents, and musical data. The international conference on information Visualisation (iV), one of the longest running on the subject has open forum philosophy of interdisciplinary drive to define its subject theme and discussion and focus group. This special issue of Multimedia Tools and Applications for Information Visualisation is based on the handful of submissions to the 22 nd International Conference on Information Visualisation (iV18), which was held in Italy in July 2018. The selected papers give examples of techniques, domains and number of case studies to address some issues. The papers presented in this Special Issue investigate different aspects of the theme highlighted above. The first set of papers [1, 2, 12, 16] investigate and evaluate the visualization of spatial, temporal and spatio-temporal data. Almeida et al. [2] consider how and why consideration of Level of Detail (LoD) plays a crucial role in analytics. They propose a Visual Analytics approach-VAST, allows users to simultaneous inspection of phenomenon using different LoDs. VAST demonstrates using LoDs will reveal different prospective and hence portraying different perception of the phenomenon.