“…Therefore, most studies in biomechanics use the second approach: empirical models. These almost always consist of polynomial expressions (including splines, which are piecewise polynomials stitched together) mapping joint angles to tendon excursions, and are regressed from experimental measurements, such as using cadaveric specimens [6], [13], [14], [8], [18], [19]. But these polynomial regressions have several inherent mathematical pitfalls; they can fail to extrapolate, may require large datasets to train, are not robust to noise, and often have numerous free parameters [20].…”