Molybdenum in Biological Samples and Clinical Significance of Serum Molybdenum

Yoshida, Minoru

doi:10.1002/9781118271858.ch14

Cited by 1 publication

(4 citation statements)

References 31 publications

(39 reference statements)

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“…https://doi.org/10.1017/S0007114522000319 Accepted manuscript Ethiopia was 0.2 μg dL -1 within the range of 0.01-2.1 μg dL -1 . This is high compared with other countries like Japan, Belgium, USA, UK, Sweden, Hungary, Germany and Zaire, that serum Mo concentration is in the range of 0.12-0.22 μg dL -1 (42) . Similar to the distribution of Co, there was no significant difference in serum Mo status among demographic groups and their residential area.…”

Section: Accepted Manuscriptmentioning

confidence: 73%

“…Mo is an important component of enzymes such as xanthine dehydrogenase, aldehyde oxidase and sulphite oxidase (41,42) . The median concentration of serum Mo in Ethiopia was 0•2 μg dl −1 within the range of 0•01-2•1 μg dl −1 .…”

Section: Discussionmentioning

confidence: 99%

“…However, there were spatial differences between regions, with Mo deficiency prevalence was 1•1 % in Amhara and 0•4 % in the Somali region. Food groups with high Mo concentrations are plant foods such as cereals, pulses, nuts and their product (41,42) . The national food consumption survey reported that most of the food sourced in Ethiopia are plant based (36) .…”

Section: Discussionmentioning

confidence: 99%

“…Molybdenum is an important component of enzymes such as xanthine dehydrogenase, aldehyde oxidase and sulfite oxidase (41,42) . The median concentration of serum Mo in Downloaded from https://www.cambridge.org/core.…”

Section: Accepted Manuscriptmentioning

confidence: 99%

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Mineral micronutrient status and spatial distribution among the Ethiopian population

et al. 2022

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Multiple micronutrient deficiencies are widespread in Ethiopia. However, the distribution of selenium and zinc deficiency risks has previously shown evidence of spatially dependent variability, warranting the need to explore this aspect for wider micronutrients. Here, blood serum concentrations for calcium (Ca), magnesium (Mg), cobalt (Co), copper (Cu), and molybdenum (Mo) were measured (n 3,102) on samples from the Ethiopian National Micronutrient Survey. Geostatistical modelling was used to test spatial variation of these micronutrients for women of reproductive age (WRA), who represent the largest demographic group surveyed (n 1,290). Median serum concentrations were 8.6 mg dL−1 for Ca, 1.9 mg dL−1 for Mg, 0.4 µg L−1 for Co, 98.8 µg dL−1 for Cu, and 0.2 µg dL−1 for Mo. The prevalence of Ca, Mg and Co deficiency was 41.6%, 29.2% and 15.9%, respectively; Cu and Mo deficiency prevalence was 7.6% and 0.3%, respectively. A higher prevalence of Ca, Cu and Mo deficiency was observed in north western, Co deficiency in central, and Mg deficiency in north eastern parts of Ethiopia. Serum Ca, Mg, and Mo concentrations show spatial dependencies up to 140–500 km; however, there was no evidence of spatial correlations for serum Co and Cu concentrations. These new data indicate the scale of multiple mineral micronutrient deficiency in Ethiopia and the geographical differences in the prevalence of deficiencies suggesting the need to consider targeted responses during the planning of nutrition intervention programs.

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Section: Accepted Manuscriptmentioning

confidence: 73%

Section: Discussionmentioning

confidence: 99%