Molluscicidal and Phytochemical Properties of Selected Medicinal Plants of Jamaica, West Indies

Ellis-Tabanor, Margelette; Robinson, Dwight R.; Hyslop, E. J.

doi:10.2174/22103155113039990007

Cited by 1 publication

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“…5,13 Following this discovery, subsequent studies in Ethiopia and elsewhere have established that the plant is a potent molluscicide. 11,[14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30] The first laboratory aided test for its molluscicidal effect was conducted by Lemma in 1970. 5 Powdered ripe berries were added to different amounts of standard water to make the desired weight by volume expressed by parts per million.…”

Section: Pharmacological Activities Molluscicidal Activitymentioning

confidence: 99%

Pharmacology, Phytochemistry, and Toxicity Profiles of Phytolacca dodecandra L’Hér: A Scoping Review

et al. 2020

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Introduction: Phytolacca dodecandra L’Hér. is a native plant of sub-Saharan Africa and Madagascar which is traditionally used for various ailments. Concerned with the scope of the available evidence, we designed a scoping review to critically analyze scientific evidence on P dodecandra’s pharmacology, toxicity, and phytochemistry to validate its ethnomedical use. Methods: We searched without language restriction in MEDLINE, Google Scholar, Scopus, Embase, and Web of Science through December 2019. Both published and unpublished articles were assessed for relevance and reviewed. Results: Of 600 articles retrieved through database search, a total of 48 articles were finally included. The butanol extract of berries was more potent molluscicidal than aqueous extract. The berries had also miracidial, anthelmintic, antifungal activity, and antibacterial effect against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, and Salmonella spp. The methanol extracts of roots had an antifungal effect against Candida albicans, Cryptococcus neoformans, Microsporum gypseum, and Trichophyton mentagrophytes. Phytolacca dodecandra was toxic to aquatic invertebrate and fish. The fishes were up to 4 times more sensitive than snails. Saponins were the main phytoconstituent isolated from berries. Terpenoid and phenolic were abundant in leaves and bark extracts. Conclusions: Studies validated the traditional use of P dodecandra against snails, worms, and various bacterial and fungal infections. Limited phytochemical data call for future research to focus on isolation of compounds; test their toxicity and activity; and establish mechanism of action.

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