Molecularly Imprinted Polymer with High Capacity and Selectivity for Separation of Bovine Serum Albumin
Meiyu Zhang,
Yafei Wang,
Keling Hu
et al.
Abstract:A cost-effective but simple method for the separation of bovine serum albumin (BSA) from complex biological fluids is still lacking. Here using N-isopropylacrylamide as the main monomer and dimethylaminoethyl methacrylate, methacrylic acid, and acrylamide as functional monomers, a BSA-imprinted polymer was synthesized. To overcome the two major obstacles of common protein-imprinted polymers, i.e., difficult template removal and low imprinting efficiency, an oligo(glutamic acid)-based peptide cross-linker with … Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.