Molecularly imprinted polymer based on CdTe@SiO₂ quantum dots as a fluorescent sensor for the recognition of norepinephrine

Abstract

A novel molecular imprinted sensor based on CdTe@SiO2 quantum dots (QDs) was developed for norepinephrine (NE) recognition. The molecularly imprinted polymer (MIP) on the surface of CdTe@SiO2 QDs (CdTe@SiO2@MIP) was characterized by Fourier transform infrared spectroscopy, transmission electron microscopy and fluorescence spectroscopy. The synthesized nanosensor had a distinguished selectivity and high binding affinity to NE. Under optimal conditions, the relative fluorescence intensity of CdTe@SiO2@MIP linearly decreased with increase of the concentration of NE in the range of 0.04-10 μM. The limit of detection was 8 nM (3σ/K). The proposed method was applied to the analysis of NE in rat plasma, and the result obtained by the method was in good agreement with that assayed by the fluorescence derivatization method. The method developed is simple, fast, and can be applied to the determination of NE in biological samples.

A sensitive fluorescent nanosensor for chloramphenicol based on molecularly imprinted polymer‐capped CdTe quantum dots

“…Wei et al . developed a sensor using the molecular imprinted polymer on the surface of the CdTe QDs for norepinephrine (NE) recognition. Zhang et al .…”

Development of a Probe Based on Quantum Dots Embedded with Molecularly Imprinted Polymers to Detect Parathion

“…6). The analyte quenches the fl uorescence of the QD in a concentration dependence in agreement with the Stern-Volmer equation as described in the literature [14,16,25]. The Stern-Volmer formula is given as:…”

“…In this work, we fabricated an imprinted silica matrix embedded with CdTe QDs, which could be adopted to monitor the target molecules by the changes of fl uorescence intensity of CdTe QDs. MIP-capped CdTe QDs were prepared via a surface molecular imprinting process similar to a previously reported procedure [16][17][18]. The O, O-diethyl, and nitrophenyl groups of parathion can form strong hydrogen bonding with the amino groups of the functional monomer to form MIP fi lm on the surface of QDs (Fig.…”

Preparation of Thermosensitive Hollow Imprinted Microspheres via Combining Distillation Precipitation Polymerization and Thiol‐ene Click Chemistry

“…MIPs have been synthesized with specific recognition ability for both chemical and biological molecules, such as drugs, [4] pollutants, [5] food ingredients, [6] amino acids and proteins, and various nucleotides. These synthetic materials, especially with the hollow micro-and nano-structures, have been widely used in separation and purification science, [7] chemical analysis and detection, catalysis, solid-phase extraction, [8] sensors, [9] and drug delivery.…”