Molecularly imprinted polymer-based electrochemical impedimetric sensors on screen-printed carbon electrodes for the detection of trace cytokine IL-1β

Choi, Doo Young; Yang, Jin Chul; Hong, Suck Won; Park, Jinyoung

doi:10.1016/j.bios.2022.114073

Cited by 28 publications

(19 citation statements)

References 31 publications

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“…Using biomimetic elements, such as MIPs, brings important benefits in increasing the selectivity of sensors. Numerous MIPs have been developed for biomedical applications 150–154 . Thus, a highly sensitive, accurate, and fast biomimetic detection device was fabricated for IL‐6 detection in human serum, the MIP film being prepared on a SPE of carbon by the co‐electropolymerization of pyrrole and carboxylated pyrrole in the presence of IL‐6 150 …”

Section: Analytical Methods Applied For Cytokines Determination In Bi...mentioning

confidence: 99%

“…A double layer comprising poly(o‐phenylenediamine), poly(chromotrope 2R) was formed to generate a MIP film at the carbon‐based SPE for the highly sensitive and selective detection of IL‐1β in complex matrix 151 …”

Section: Analytical Methods Applied For Cytokines Determination In Bi...mentioning

confidence: 99%

“…Numerous MIPs have been developed for biomedical applications. [150][151][152][153][154] Thus, a highly sensitive, accurate, and fast biomimetic detection device was fabricated for IL-6 detection in human serum, the MIP A double layer comprising poly(o-phenylenediamine), poly(chromotrope 2R) was formed to generate a MIP film at the carbon-based SPE for the highly sensitive and selective detection of IL-1β in complex matrix. 151 The detection of a single cytokine biomarker cannot be used for diagnostic purposes for a particular condition, given that these compounds are expressed in several pathologies.…”

Section: Electrochemical Sensorsmentioning

confidence: 99%

“…[150][151][152][153][154] Thus, a highly sensitive, accurate, and fast biomimetic detection device was fabricated for IL-6 detection in human serum, the MIP A double layer comprising poly(o-phenylenediamine), poly(chromotrope 2R) was formed to generate a MIP film at the carbon-based SPE for the highly sensitive and selective detection of IL-1β in complex matrix. 151 The detection of a single cytokine biomarker cannot be used for diagnostic purposes for a particular condition, given that these compounds are expressed in several pathologies. 155,156 Finding multiple biomarkers that can be detected simultaneously with a sensor or by using arrays of sensors, can provide the specificity needed to use the detection result for diagnostic purposes.…”

Section: Electrochemical Sensorsmentioning

confidence: 99%

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Unrevealing the connection between real sample analysis and analytical method. The case of cytokines

Irimes

Tertiş

Oprean

et al. 2023

Medicinal Research Reviews

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Cytokines are compounds that belong to a special class of signaling biomolecules that are responsible for several functions in the human body, being involved in cell growth, inflammatory, and neoplastic processes. Thus, they represent valuable biomarkers for diagnosing and drug therapy monitoring certain medical conditions. Because cytokines are secreted in the human body, they can be detected in both conventional samples, such as blood or urine, but also in samples less used in medical practice such as sweat or saliva. As the importance of cytokines was identified, various analytical methods for their determination in biological fluids were reported. The gold standard in cytokine detection is considered the enzyme‐linked immunosorbent assay method and the most recent ones have been considered and compared in this study. It is known that the conventional methods are accompanied by a few disadvantages that new methods of analysis, especially electrochemical sensors, are trying to overcome. Electrochemical sensors proved to be suited for the elaboration of integrated, portable, and wearable sensing devices, which could also facilitate cytokines determination in medical practice.

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Section: Analytical Methods Applied For Cytokines Determination In Bi...mentioning

confidence: 99%

Section: Analytical Methods Applied For Cytokines Determination In Bi...mentioning

confidence: 99%

Section: Electrochemical Sensorsmentioning

confidence: 99%

Section: Electrochemical Sensorsmentioning

confidence: 99%

See 2 more Smart Citations

Unrevealing the connection between real sample analysis and analytical method. The case of cytokines

Irimes

Tertiş

Oprean

et al. 2023

Medicinal Research Reviews

View full text Add to dashboard Cite

show abstract

“…In addition, MIP materials have demonstrated several important benefits in electrochemical sensors including (i) easy preparation, (ii) low cost, (iii) storage stability, (iv) repeated use without deterioration of performance, and (v) resistance to pressure, heat, and harsh chemical conditions. 3–6 These benefits have enabled MIP based electrochemical sensors to fulfil the needs of the development of standard analytical techniques, which can be used in day-to-day experiments while also achieving good performance for numerous repetitions.…”

Section: Introductionmentioning

confidence: 99%