Molecular targets associated with ulcerative colitis and the benefits of atractylenolides-based therapy
Huanzhu Qian,
Zhen Ye,
Yu Hu
et al.
Abstract:Ulcerative colitis (UC) is a chronic inflammatory disease of the intestines that can significantly impact quality of life and lead to various complications. Currently, 5-aminosalicylic acid derivatives, corticosteroids, immunosuppressants, and biologics are the major treatment strategies for UC, but their limitations have raised concerns. Atractylenolides (ATs), sesquiterpene metabolites found in Atractylodes macrocephala Koidz., have shown promising effects in treating UC by exerting immune barrier modulation… Show more
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