Molecular Survey on Leishmania Infantum Infection in Red Foxes (Vulpes Vulpes) From Romania

Ionică, Angela Monica; Deak, Georgiana; Kalmár, Zsuzsa; Gherman, Călin Mircea; Mihalca, Andrei Daniel; Dumitrache, Mirabela Oana

doi:10.15835/buasvmcn-vm:0054

Cited by 3 publications

(3 citation statements)

References 11 publications

(14 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…After 2005, 16 other human cases have been reported in Romania [ 10 - 14 ], most of which involved patients living in the SE of the country, which correlates with local climatic conditions and the high infestation rates that were found in dogs from that area [ 15 ].…”

Section: Discussionmentioning

confidence: 99%

Subconjunctival ocular filariasis -Case report-

Macarie¹,

Dobre²,

Suciu³

et al. 2017

rjo

View full text Add to dashboard Cite

We are presenting the case of a patient who was clinically diagnosed with subconjunctival ocular dirofilariasis, confirmed by the parasitological examination. The treatment consisted in the surgical extraction of the parasite, a local treatment with antibiotics and steroidal anti-inflammatory mydriatic and general treatment with antihelminthic, antibiotic, analgesic, and anti-inflammatory drugs. The intraoperative and postoperative evolution of the case was favorable.

show abstract

Section: Discussionmentioning

confidence: 99%

Subconjunctival ocular filariasis -Case report-

Macarie¹,

Dobre²,

Suciu³

et al. 2017

rjo

View full text Add to dashboard Cite

show abstract

“…All these clues have prompted testing the efficiency of the conjunctival swab for CVL diagnosis [264][265][266][267] and tracking asymptomatic dog infections [268] but also for diagnosing feline leishmaniasis [267,269,270]. In addition, the detection of Leishmania DNA in conjunctival swabs has also been applied to track L. infantum wild reservoirs [271,272].…”

Section: Conjunctival Swab/lacrimal Fluid/occularmentioning

confidence: 99%

Noninvasive Biological Samples to Detect and Diagnose Infections due to Trypanosomatidae Parasites: A Systematic Review and Meta-Analysis

Sereno

Akhoundi

Sayehmri

et al. 2020

IJMS

View full text Add to dashboard Cite

Unicellular eukaryotes of the Trypanosomatidae family include human and animal pathogens that belong to the Trypanosoma and Leishmania genera. Diagnosis of the diseases they cause requires the sampling of body fluids (e.g., blood, lymph, peritoneal fluid, cerebrospinal fluid) or organ biopsies (e.g., bone marrow, spleen), which are mostly obtained through invasive methods. Body fluids or appendages can be alternatives to these invasive biopsies but appropriateness remains poorly studied. To further address this question, we perform a systematic review on clues evidencing the presence of parasites, genetic material, antibodies, and antigens in body secretions, appendages, or the organs or proximal tissues that produce these materials. Paper selection was based on searches in PubMed, Web of Science, WorldWideScience, SciELO, Embase, and Google. The information of each selected article (n = 333) was classified into different sections and data were extracted from 77 papers. The presence of Trypanosomatidae parasites has been tracked in most of organs or proximal tissues that produce body secretions or appendages, in naturally or experimentally infected hosts. The meta-analysis highlights the paucity of studies on human African trypanosomiasis and an absence on animal trypanosomiasis. Among the collected data high heterogeneity in terms of the I 2 statistic (100%) is recorded. A high positivity is recorded for antibody and genetic material detection in urine of patients and dogs suffering leishmaniasis, and of antigens for leishmaniasis and Chagas disease. Data on conjunctival swabs can be analyzed with molecular methods solely for dogs suffering canine visceral leishmaniasis. Saliva and hair/bristles showed a pretty good positivity that support their potential to be used for leishmaniasis diagnosis. In conclusion, our study pinpoints significant gaps that need to be filled in order to properly address the interest of body secretion and hair or bristles for the diagnosis of infections caused by Leishmania and by other Trypanosomatidae parasites.

show abstract

“…All these clues have prompted testing the efficiency of the conjunctival swab for CVL diagnosis [256][257][258][259] and tracking asymptomatic dog infections [260] but also for diagnosing feline leishmaniasis [259,261,262]. In addition, the detection of Leishmania DNA in conjunctival swabs has also been applied to track L. infantum wild reservoirs [263,264].…”

Section: Conjunctival Swab/lacrimal Fluid/occularmentioning

confidence: 99%

Noninvasive Biological Samples to Detect and Diagnose Infections due to Trypanosomatidae Parasites: A Systematic Review and Meta-Analysis

Sereno¹,

Akhoundi²,

Sayehmri³

et al. 2020

Preprint

View full text Add to dashboard Cite

Unicellular eukaryotes of the Trypanosomatidae family include human and animal pathogens that belong to the Trypanosoma and Leishmania genera. Diagnosis of the diseases they caused requires the sampling of body fluids (blood, lymph, peritoneal fluid, cerebrospinal fluid, etc.) or organ biopsies (bone marrow, spleen, etc.), which are mostly obtained through invasive methods. Body fluids or appendages can be alternatives to these invasive biopsies but appropriateness remains poorly studied. To further address this question, we perform a systematic review on clues evidencing the presence of parasites, genetic material, antibodies, and antigens in body secretions, appendages, or the organs or proximal tissues that produce these materials. Paper selection was based on searches in PubMed, Web of Science, WorldWideScience, SciELO, Embase, Google. The information of each selected article (n=333) was classified into different sections and data were extracted from 77 papers. The presence of Trypanosomatidae parasites has been tracked in most of organs or proximal tissues that produce body secretions or appendages, in naturally or experimentally infected hosts. The meta-analysis highlights the paucity of studies on Human African Trypanosomiasis and a the absence on animal Trypanosomiasis. Among the collected data high heterogeneity in terms of the I2 statistic (100%) is recorded. A high positivity is recorded for antibody and genetic material detection in urine of patients and dogs suffering leishmaniasis, and of antigen for leishmaniasis and Chagas disease. Data on conjunctival swab can be analyzed with molecular methods solely for dogs suffering canine visceral leishmaniasis. Saliva and hair/bristle showed a pretty good positivity that support their potential to be used for leishmaniasis diagnosis. In conclusion, our study pinpoints significant gaps that need to be filled in order to properly address the interest of body secretion and hair or bristle for the diagnosis of infections caused by Leishmania and by other Trypanosomatidae parasites.

show abstract

Molecular Survey on Leishmania Infantum Infection in Red Foxes (Vulpes Vulpes) From Romania

Cited by 3 publications

References 11 publications

Subconjunctival ocular filariasis -Case report-

Subconjunctival ocular filariasis -Case report-

Noninvasive Biological Samples to Detect and Diagnose Infections due to Trypanosomatidae Parasites: A Systematic Review and Meta-Analysis

Noninvasive Biological Samples to Detect and Diagnose Infections due to Trypanosomatidae Parasites: A Systematic Review and Meta-Analysis

Contact Info

Product

Resources

About