“…3,4 Signicant research effort is focussed on developing synthetic receptors for nucleoside phosphate anions, due to the critical roles they play in biological processes, including energy transduction, phosphorylation, cellular signalling and DNA synthesis. 5,6 The creation of receptors capable of binding and differentiating nucleoside phosphate anions (e.g. ATP, ADP, AMP, GTP, GDP, UDP) under physiological conditions could underpin exciting new sensing tools for biomedical research and drug discovery, 7 but it is very challenging due to the similarities in anion structure, size and charge.…”