Molecular perspectives on systemic priming and concomitant immunity in colorectal carcinoma
Suman Kumar Ray,
Sukhes Mukherjee
Abstract:The progression of metastasis, a complex systemic disease, is facilitated by interactions between tumor cells and their isolated microenvironments. Over the past few decades, researchers have investigated the metastatic spread of cancer extensively, identifying multiple stages in the process, such as intravasation, extravasation, tumor latency, and the development of micrometastasis and macrometastasis. The premetastatic niche is established in target organs by the accumulation of aberrant immune cells and ext… Show more
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