Molecular methods enhance the detection of pyoderma-related Streptococcus pyogenes and emm-type distribution in children
Jennifer Natalie Hall,
Edwin P. Armitage,
Elina Senghore
et al.
Abstract:Background: Streptococcus pyogenes-related skin infections are increasingly implicated in the development of rheumatic heart disease (RHD) in lower-resourced settings, where they are often associated with scabies. The true prevalence of S. pyogenes-related pyoderma may be underestimated by bacterial culture. Methods: A multiplex qPCR for S. pyogenes, Staphylococcus aureus and Sarcoptes scabiei was applied to 250 pyoderma swabs from a cross-sectional study of children <5 years in The Gambia. Direct PCR-based… Show more
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