Abstract:Mitophagy is a selective autophagy process in which damaged or surplus mitochondria are removed to sustain normal homeostasis. The efficient removal of damaged or stressed mitochondria is crucial for cellular health. Recent literature emphasizes the role of PINK1-Parkin pathways in the pathogenesis process of various neurodegenerative disorders. Further, mitophagy has shown potential therapeutic activity in treating neurodegenerative diseases. Thus, mitophagy might be important in the field of pharmacotherapeu… Show more
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