2024
DOI: 10.20944/preprints202401.1611.v1
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Molecular Mechanisms of Nuclear Import of Baculovirus Proteins

Jia-Le Li,
Xing-Yang Wang,
Xiao-Feng Wu

Abstract: Baculovirus is a type of virus with a double stranded, circular, and super helical DNA structure, whose transcription, replication and assembly of offspring virus occur in the nucleus of the cell. However, due to the natural barrier of the cellular nuclear membrane, macromolecular substances larger than 40-60 kDa cannot directly penetrate the nuclear membrane. Therefore, baculovirus have evolved various strategies to achieve transmembrane transport of viral proteins. This article attempts to review the recent … Show more

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