Molecular mechanisms of heavy metals resistance of Stenotrophomonas rhizophila JC1 by whole genome sequencing

Sun, Shangchen; Chen, Jixiang; Wang, Yonggang; Leng, Feifan; Zhao, Jian; Chen, Kai; Zhang, Qing‐Chun

doi:10.1007/s00203-021-02271-0

Cited by 13 publications

(3 citation statements)

References 32 publications

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“…In the czcCBA operon, czcC is an outer membrane protein, czcB is a membrane fusion protein, czcA is responsible for Co-Zn-Cd transportation, and czcD is a regulatory protein. Thus, the czcCBA operon along with downstream gene czcD mediates the detoxi cation of Zn 2+ , which is consistent with the permafrost strain's resistance to Zn 2+ (Sun et al 2021). Chromate reductase (chrR) reduces Cr 6+ (Ackerley et al…”

Section: Mic Of Metals and Mrgssupporting

confidence: 65%

Antibiotic and metal resistance of Stenotrophomonas maltophilia isolates from Eboling permafrost of the Tibetan Plateau

Zhang

Yang

Jiang

2022

Environ Sci Pollut Res

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There is a growing concern about antibiotic and metal resistance in natural and clinical settings. This study examined antibiotic and metal resistance for ancient Stenotrophomonas maltophilia isolated from permafrost. Whole-genome sequencing was applied to examine antibiotic resisrance genes and metal resistance genes. The permafrost S. maltophilia exhibited resistance to chloramphenicol, trimethoprim-sulfamethoxazole, and erythromycin, which is consistent with the presence of multidrug e ux pump smeDEF. The absence of qnrB, qnrR, oqxB, and smrA is consistent with its sensitivity for tetracycline, and cipro oxacin. Also, the absence of bcrABC is consistent with the strain's sensitivity to bacitracin. The strain also showed metal resistance to Zn 2+ , Cu 2+ , Cr 6+ , Hg 2+ , which is consistent with the presence of czcABCD, cueR and copA, chrR, merT, and merD. The strain showed worse resistance (lower MICs) to cipro oxacin, tetracycline, chloramphenicol, trimethoprim/sulfamethoxazole, and 4 metals Zn 2+ , Ni 2+ , Cu 2+ , and Cr 6+ , compared with clinical S. maltophilia; the former strain belongs to the lower ARG and MRG gene clusters compared to latter one. Among 12 genomic islands (GIs) in the permafrost strain, 5 contained resistance genes, with only one kind of ARG or MRG, while S. maltophilia from other environments exhibited a minimum of 2 kinds of resistance gene clustering on a single GI. This study demonstrates that continuous exposure to the clinical environment can create a selective pressure on bacteria inducing resistance to antibiotics and metals, involving more ARGs and MRGs via horizontal gene transfer route.

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Section: Mic Of Metals and Mrgssupporting

confidence: 65%

Antibiotic and metal resistance of Stenotrophomonas maltophilia isolates from Eboling permafrost of the Tibetan Plateau

Zhang

Yang

Jiang

2022

Environ Sci Pollut Res

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“…Microbes also reduce the concentration of HMs in soil; for instance, Aspergillus niger showed an appreciable ability to for bioaccumulation of Cd and Cr ( Khan et al., 2019 ), similarly, Stenotrophomonas rhizophila also significantly removed Pb and Cu by 76.9% and 83.4% ( Sun et al., 2021 ). Due to small size microbes also provide a large surface area to adsorb the HMs which reduces the overall availability of HMs ( Rajput et al., 2022 ).…”

Section: Introductionmentioning

confidence: 99%

Microbial mediated remediation of heavy metals toxicity: mechanisms and future prospects

Tang,

Xiang,

Xiao

et al. 2024

Front. Plant Sci.

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Heavy metal pollution has become a serious concern across the globe due to their persistent nature, higher toxicity, and recalcitrance. These toxic metals threaten the stability of the environment and the health of all living beings. Heavy metals also enter the human food chain by eating contaminated foods and cause toxic effects on human health. Thus, remediation of HMs polluted soils is mandatory and it needs to be addressed at higher priority. The use of microbes is considered as a promising approach to combat the adverse impacts of HMs. Microbes aided in the restoration of deteriorated environments to their natural condition, with long-term environmental effects. Microbial remediation prevents the leaching and mobilization of HMs and they also make the extraction of HMs simple. Therefore, in this context recent technological advancement allowed to use of bioremediation as an imperative approach to remediate polluted soils. Microbes use different mechanisms including bio-sorption, bioaccumulation, bioleaching, bio-transformation, bio-volatilization and bio-mineralization to mitigate toxic the effects of HMs. Thus, keeping in the view toxic HMs here in this review explores the role of bacteria, fungi and algae in bioremediation of polluted soils. This review also discusses the various approaches that can be used to improve the efficiency of microbes to remediate HMs polluted soils. It also highlights different research gaps that must be solved in future study programs to improve bioremediation efficency.

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“…For example, Aspergillus niger M1DGR, which was isolated from the industrial soil of Hattar, Pakistan, demonstrated extremely high bioaccumulation; it was able to extract 98% Cd and 43% Cr [35]. Stenotrophomonas rhizophila JC, isolated from the contaminated soil of Jinchang (China), was able to remove 76.9% Pb and 83.4% Cu [36].…”

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confidence: 99%

Microorganisms for Bioremediation of Soils Contaminated with Heavy Metals

et al. 2023

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Heavy-metal contaminants are one of the most relevant problems of contemporary agriculture. High toxicity and the ability to accumulate in soils and crops pose a serious threat to food security. To solve this problem, it is necessary to accelerate the pace of restoration of disturbed agricultural lands. Bioremediation is an effective treatment for agricultural soil pollution. It relies on the ability of microorganisms to remove pollutants. The purpose of this study is to create a consortium based on microorganisms isolated from technogenic sites for further development in the field of soil restoration in agriculture. In the study, promising strains that can remove heavy metals from experimental media were selected: Pantoea sp., Achromobacter denitrificans, Klebsiella oxytoca, Rhizobium radiobacter, and Pseudomonas fluorescens. On their basis, consortiums were compiled, which were investigated for the ability to remove heavy metals from nutrient media, as well as to produce phytohormones. The most effective was Consortium D, which included Achromobacter denitrificans, Klebsiella oxytoca, and Rhizobium radiobacter in a ratio of 1:1:2, respectively. The ability of this consortium to produce indole-3-acetic acid and indole-3-butyric acid was 18.03 μg/L and 2.02 μg/L, respectively; the absorption capacity for heavy metals from the experimental media was Cd (56.39 mg/L), Hg (58.03 mg/L), As (61.17 mg/L), Pb (91.13 mg/L), and Ni (98.22 mg/L). Consortium D has also been found to be effective in conditions of mixed heavy-metal contamination. Due to the fact that the further use of the consortium will be focused on the soil of agricultural land cleanup, its ability to intensify the process of phytoremediation has been studied. The combined use of Trifolium pratense L. and the developed consortium ensured the removal of about 32% Pb, 15% As, 13% Hg, 31% Ni, and 25% Cd from the soil. Further research will be aimed at developing a biological product to improve the efficiency of remediation of lands withdrawn from agricultural use.

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Molecular mechanisms of heavy metals resistance of Stenotrophomonas rhizophila JC1 by whole genome sequencing

Cited by 13 publications

References 32 publications

Antibiotic and metal resistance of Stenotrophomonas maltophilia isolates from Eboling permafrost of the Tibetan Plateau

Antibiotic and metal resistance of Stenotrophomonas maltophilia isolates from Eboling permafrost of the Tibetan Plateau

Microbial mediated remediation of heavy metals toxicity: mechanisms and future prospects

Microorganisms for Bioremediation of Soils Contaminated with Heavy Metals

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