Molecular Mechanisms of Drug Resistance in Leishmania spp.
Maria Juliana Moncada-Diaz,
Cristian Camilo Rodríguez-Almonacid,
Eyson Quiceno-Giraldo
et al.
Abstract:The protozoan parasite Leishmania causes leishmaniasis, a neglected tropical disease, that disproportionately affects underdeveloped countries. This disease has major health, economic, and social implications, particularly because of the limited treatment options, high cost, the severe side effects associated with available therapeutics, and the high rate of treatment failure caused by the parasites’ growing resistance to current medications. In this review, we describe first the common strategies used by path… Show more
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