Molecular mechanisms and potential therapeutic targets in the pathogenesis of hypertension in visceral adipose tissue induced by a high-fat diet
Zhenyang Su,
Jin-Yu Sun,
Min Gao
et al.
Abstract:BackgroundHypertension (HTN) presents a significant global public health challenge with diverse causative factors. The accumulation of visceral adipose tissue (VAT) due to a high-fat diet (HFD) is an independent risk factor for HTN. While various studies have explored pathogenic mechanisms, a comprehensive understanding of impact of VAT on blood pressure necessitates bioinformatics analysis.MethodsDatasets GSE214618 and GSE188336 were acquired from the Gene Expression Omnibus and analyzed to identify shared di… Show more
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