Molecular mechanism of Xiaohuoluo wan for rheumatoid arthritis by integrating in vitro and in vivo chemomics and network pharmacology
Wanli Qin,
Kai Zhang,
Ziyang Yu
et al.
Abstract:The cause of rheumatoid arthritis (RA) is unclear. Xiaohuoluo wan (XHLW) is a classical Chinese medicine that is particularly effective in the treatment of RA. Given the chemical composition of XHLW at the overall level has been little studied and the molecular mechanism for the treatment of RA is not clear, we searched for the potential active compounds of XHLW and explored their anti‐inflammatory mechanism in the treatment of RA by flexibly integrating the high‐resolution ultra‐performance liquid chromatogra… Show more
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