Molecular mechanism of autophagy and apoptosis in endometriosis: Current understanding and future research directions
Hiroshi Kobayashi,
Shogo Imanaka,
Chiharu Yoshimoto
et al.
Abstract:BackgroundEndometriosis is a common gynecological condition, with symptoms including pain and infertility. Regurgitated endometrial cells into the peritoneal cavity encounter hypoxia and nutrient starvation. Endometriotic cells have evolved various adaptive mechanisms to survive in this inevitable condition. These adaptations include escape from apoptosis. Autophagy, a self‐degradation system, controls apoptosis during stress conditions. However, to date, the mechanisms regulating the interplay between autopha… Show more
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