Molecular Markers and Mechanisms of Influenza A Virus Cross-Species Transmission and New Host Adaptation
Xinyi Guo,
Yang Zhou,
Huijun Yan
et al.
Abstract:Influenza A viruses continue to be a serious health risk to people and result in a large-scale socio-economic loss. Avian influenza viruses typically do not replicate efficiently in mammals, but through the accumulation of mutations or genetic reassortment, they can overcome interspecies barriers, adapt to new hosts, and spread among them. Zoonotic influenza A viruses sporadically infect humans and exhibit limited human-to-human transmission. However, further adaptation of these viruses to humans may result in… Show more
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