Molecular karyotype of clone CL Brener chosen for the Trypanosoma cruzi Genome Project

Molecular karyotype and chromosomal localization of genes encoding ß-tubulin, cysteine proteinase, hsp 70 and actin in Trypanosoma rangeli

“…Also, chromosomal bands over 5700 Kb were observed as previously reported (Henriksson et al 1996b) (data not shown). The absence of such large chromosomes in the T. cruzi reference clone is in agreement with other authors findings (Cano et al 1995.…”

“…Housekeeping genes fragments or anonymous markers have been used as probes to map T. cruzi chromosomes (Cano et al 1995). Some of these DNA probes have shown to be useful markers to distinguish T. cruzi from T. rangeli strains (Henriksson et al 1996b).…”

“…Molecular karyotyping associated with gene localization within chromosomes has been used as tools for identification and characterization of isolates and clones of trypanosomatids (Cano et al 1995, Henriksson et al 1996a. On this field, Henriksson et al (1996b) have analyzed a reasonable number of T. rangeli samples using molecular karyotyping.…”

Chagas disease, from discovery to control - and beyond: history, myths and lessons to take home

“…The T. cruzi genome project, which matured in several meetings in 1993 and 1994 and was officially launched in 1994 in a TDR-Fiocruz co-sponsored meeting held at Fiocruz's headquarters in Rio de Janeiro, is now well under way through the concerted action of more than 20 laboratories, most of them in the South (Cano et al 1995, Zingales et al 1997a,b,c, Brandão et al 1997, Ferrari et al 1997, Degrave et al 1997a.…”

Organization and expression of a multigene family encoding the surface glycoproteins of Trypanosoma cruzi metacyclic trypomastigotes involved in the cell invasion

“…Gp90 and gp82 are present in multiple copies, distributed in several chromosomes, and this gene family can be divided into subsets on the basis of hybridization patterns obtained with probes derived from different regions of gp90 and gp82 genes (Araya et al 1994, Cano et al 1995. Many members of gp90 and gp82 gene family are closely linked to members of gp85/sialidase family at multiple sites in the genome of different T. cruzi strains.…”