Molecular interactions of active constituents of essential oils in zwitterionic lipid bilayers

Saha, Sarmistha; Verma, Richa

doi:10.1016/j.chemphyslip.2018.03.008

Cited by 4 publications

(1 citation statement)

References 33 publications

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“…The physical state of the lipid bilayer depends on the strength of Van der Waals interactions between adjacent lipids [32], it seems that the interaction of some EO components with the lipids could contribute to the energy needed to disrupt the interactions, resulting in a more fluid state of the membrane. [37,38] Besides the changes in the Tm, the cooperativity, which measures the sharpness of the phase transition, is very sensitive to the presence of any additive in the lipid bilayer [39]. In this sense, following the changes in the cooperative also gives information on the changes induced in the bilayer.…”

Section: J O U R N a L P R E -P R O O Fmentioning

confidence: 99%

Antimicrobial properties of the essential oil of Schinus areira (Aguaribay) against planktonic cells and biofilms of S. aureus

Cutró

Coria

Bordón

et al. 2023

Archives of Biochemistry and Biophysics

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Section: J O U R N a L P R E -P R O O Fmentioning

confidence: 99%

Antimicrobial properties of the essential oil of Schinus areira (Aguaribay) against planktonic cells and biofilms of S. aureus

Cutró

Coria

Bordón

et al. 2023

Archives of Biochemistry and Biophysics

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Oxidation degree of a cell membrane model and its response to structural changes, a coarse-grained molecular dynamics approach

Aceves-Luna

Glossman‐Mitnik

Flores-Holgúın

2020

Journal of Biomolecular Structure and Dynamics

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Essential Oil from the Twigs of Cinnamomum Cassia Mediated the Flexible Liposomes of the Total Glucosides of Peony for Arthritis Treatment

Ding,

Liu,

Zhang

et al. 2023

j biomed nanotechnol

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Flexible liposomes (FL) have been developed as novel transdermal delivery systems. However, the skin barrier impairs the drug penetration and absorption. In this study, we designed, characterized and evaluated a total glucosides of Paeony (TPG) loaded FL (TFL) topically drug deliver system for arthritis treatment. The novelty is that the essential oil from the Twigs of Cinnamomum Cassia (EOCC) was incorporated in TFL as drug penetrating enhancer. Interestingly, the EOCC addition didn’t significantly change the characteristic parameters of the TFL in terms of morphology, size distribution, zeta potential, and entrapment efficiency. Remarkably, EOCC-embedded TGP-loaded FL (EOCC-TFL) dramatically prevented the drug leakage and improved the TGP skin penetration in vitro (4.6, 1.8, and 1.5 times higher than the TGP solution, TGP and EOCC mixture, and TFL, respectively). Moreover, despite of the low dose (175 mg/kg which was half dose of the TGP gavage group), this optimized formulation exhibited favorable anti-inflammatory effects in vivo on arthritis rats with significantly reduced swollen toe volume and serum inflammatory factor levels. This study lays solid foundation for the engineering liposomes with EOCC for transdermal drug delivery.

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Molecular interactions of active constituents of essential oils in zwitterionic lipid bilayers

Cited by 4 publications

References 33 publications

Antimicrobial properties of the essential oil of Schinus areira (Aguaribay) against planktonic cells and biofilms of S. aureus

Antimicrobial properties of the essential oil of Schinus areira (Aguaribay) against planktonic cells and biofilms of S. aureus

Oxidation degree of a cell membrane model and its response to structural changes, a coarse-grained molecular dynamics approach

Essential Oil from the Twigs of Cinnamomum Cassia Mediated the Flexible Liposomes of the Total Glucosides of Peony for Arthritis Treatment

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