Molecular insights into the loading and dynamics of anticancer drugs on silicene and folic acid-conjugated silicene nanosheets: DFT calculation and MD simulation

Conjugation of a smart polymer to doxorubicin through a pH-responsive bond for targeted drug delivery and improving drug loading on graphene oxide

“…1,2 The design of new platforms, as DDSs by using different types of nanocarriers such as polymers, metal nanoparticles, nanostructures, and nanotubes, has attracted much interest in the targeted treatment of cancer. [3][4][5] Compared to free drugs, DDSs act more efficiently and intelligently and also can diffuse more easily into cell membranes. 1,2 For example, graphene is one of the promising nanoparticles that has attracted a lot of attention due to its unique structure and biomedical properties.…”

Insights into glyphosate removal efficiency using a new 2D nanomaterial

“…The unsaturation effect at the extremes of the SNS is damped by adding hydrogen atoms at the edges. 30 …”

“…The unsaturation effect at the extremes of the SNS is damped by adding hydrogen atoms at the edges. 30 The structural data le for the GLY molecule is taken from the PubChem (PubChem CID: 3496) database. 31 The rst complex (system-A) is elaborated by manually positioning a GLY molecule around the SNS structure with a distance of $2 nm to avoid initial GLY-SNS interactions (Fig.…”

Surface functionalization of graphene nanosheet with poly (l-histidine) and its application in drug delivery: covalent vs non-covalent approaches

“…The advantages of drug DDSs include maintaining delivering multiple drugs with one formulation, the concentration of the drug for a specified period, the ability to deliver the drug to the specific site, and adjusting the rate of the drug release at the target tissue 9 . These systems reduce the toxicity and side effects of the drugs on healthy organs and increase the therapeutic effects by delivering the drug to the desired location 10 . Besides, in the DDSs, the biological and physical properties of the drug are preserved until it achieves the desired tissue.…”