Molecular Imprinting-Based Sensing Platforms for Recognition of Microorganisms

İdil, Neslihan; Bakhshpour, Monireh; Perçin, Işık; Mattìasson, Bo; Deni̇zli̇, Adil

doi:10.1016/b978-0-12-822117-4.00010-1

Cited by 5 publications

(4 citation statements)

References 77 publications

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Section: Mip-based Biomimetic Sensors For Sars-cov-2 Detectionmentioning

confidence: 99%

“…The recognition of analytes by MIPs has been coupled with a broad variety of transducers, among which electrochemical and optical transduction systems clearly dominate [ 19 , 20 , 104 , 136 , 137 , 138 ]. Nevertheless, for virus sensing, piezoelectric transducers find a wider application [ 136 ]. However, to the best of our knowledge, a QCM-based MIP sensor for the detection of SARS-CoV-2 has not been reported in the literature up to now.…”

Section: Mip-based Biomimetic Sensors For Sars-cov-2 Detectionmentioning

confidence: 99%

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Molecularly Imprinted Polymer-Based Sensors for SARS-CoV-2: Where Are We Now?

Yarman

Kurbanoğlu

2022

Biomimetics

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Since the first reported case of COVID-19 in 2019 in China and the official declaration from the World Health Organization in March 2021 as a pandemic, fast and accurate diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has played a major role worldwide. For this reason, various methods have been developed, comprising reverse transcriptase-polymerase chain reaction (RT-PCR), immunoassays, clustered regularly interspaced short palindromic repeats (CRISPR), reverse transcription loop-mediated isothermal amplification (RT-LAMP), and bio(mimetic)sensors. Among the developed methods, RT-PCR is so far the gold standard. Herein, we give an overview of the MIP-based sensors utilized since the beginning of the pandemic.

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Section: Mip-based Biomimetic Sensors For Sars-cov-2 Detectionmentioning

confidence: 99%

Section: Mip-based Biomimetic Sensors For Sars-cov-2 Detectionmentioning

confidence: 99%

Molecularly Imprinted Polymer-Based Sensors for SARS-CoV-2: Where Are We Now?

Yarman

Kurbanoğlu

2022

Biomimetics

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“…Microbial and viral imprints are also more complex, and their specific surface structures have specific requirements for recognition elements. For the capture of microorganisms, molecular imprinting can be applied to construct polymers with specific binding sites for specific cell membrane/wall components or cell membrane/wall groups [ 84 ]. Microbial recognition by MIPs can be divided into two parts, including whole-cell-based molecular imprinting strategies and cell wall component (proteins, lipids, glycans) imprinting strategies.…”

Section: Introductionmentioning

confidence: 99%

Molecularly Imprinted Nanomaterials with Stimuli Responsiveness for Applications in Biomedicine

et al. 2023

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The review aims to summarize recent reports of stimuli-responsive nanomaterials based on molecularly imprinted polymers (MIPs) and discuss their applications in biomedicine. In the past few decades, MIPs have been proven to show widespread applications as new molecular recognition materials. The development of stimuli-responsive nanomaterials has successfully endowed MIPs with not only affinity properties comparable to those of natural antibodies but also the ability to respond to external stimuli (stimuli-responsive MIPs). In this review, we will discuss the synthesis of MIPs, the classification of stimuli-responsive MIP nanomaterials (MIP-NMs), their dynamic mechanisms, and their applications in biomedicine, including bioanalysis and diagnosis, biological imaging, drug delivery, disease intervention, and others. This review mainly focuses on studies of smart MIP-NMs with biomedical perspectives after 2015. We believe that this review will be helpful for the further exploration of stimuli-responsive MIP-NMs and contribute to expanding their practical applications especially in biomedicine in the near future.

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“…SPR sensors have been used widely to detect a variety of biomolecules due to their simplicity and other advantages [ 5 ]. In recent years, SPR sensors, which can measure the change in microscopic refractive index, have been increasingly used in the field of food analysis [ 6 , 7 , 8 ]. However, the development of high-throughput, highly sensitive, cost-effective methods to be used for in situ detection of food contaminants is still limited [ 9 , 10 , 11 ].…”

Section: Introductionmentioning

confidence: 99%

Selective Detection of Penicillin G Antibiotic in Milk by Molecularly Imprinted Polymer-Based Plasmonic SPR Sensor

et al. 2021

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Molecularly imprinted polymer-based surface plasmon resonance sensor prepared using silver nanoparticles was designed for the selective recognition of Penicillin G (PEN-G) antibiotic from both aqueous solution and milk sample. PEN-G imprinted sensors (NpMIPs) SPR sensor was fabricated using poly (2-hydroxyethyl methacrylate-N-methacroyl-(L)-cysteine methyl ester)-silver nanoparticles-N-methacryloyl-L-phenylalanine methyl ester polymer by embedding silver nanoparticles (AgNPs) into the polymeric film structure. In addition, a non-imprinted (NpNIPs) SPR sensor was prepared by utilizing the same polymerization recipe without addition of the PEN-G template molecule to evaluate the imprinting effect. FTIR-ATR spectrophotometer, ellipsometer, contact angle measurements were used for the characterization of NpMIPs SPR sensors. The linear concentration range of 0.01–10 ng/mL PEN-G was studied for kinetic analyses. The augmenting effect of AgNPs used to increase the surface plasmon resonance signal response was examined using polymer-based PEN-G imprinted (MIPs) sensor without the addition of AgNPs. The antibiotic amount present in milk chosen as a real sample was measured by spiking PEN-G into the milk. According to the Scatchard, Langmuir, Freundlich and Langmuir–Freundlich adsorption models, the interaction mechanism was estimated to be compatible with the Langmuir model.

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Molecular Imprinting-Based Sensing Platforms for Recognition of Microorganisms

Cited by 5 publications

References 77 publications

Molecularly Imprinted Polymer-Based Sensors for SARS-CoV-2: Where Are We Now?

Molecularly Imprinted Polymer-Based Sensors for SARS-CoV-2: Where Are We Now?

Molecularly Imprinted Nanomaterials with Stimuli Responsiveness for Applications in Biomedicine

Selective Detection of Penicillin G Antibiotic in Milk by Molecularly Imprinted Polymer-Based Plasmonic SPR Sensor

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