Molecular imprinted polymer films on RFID tags: a first step towards disposable packaging sensors

Abstract

Phone: þ32 11 26 88 04, Fax: þ32 11 26 88 99 Web: http://www.uhasselt.be/IMO Molecular imprinted polymer (MIP) sensors offer a high potential in the development of cheap small-scale disposable biomimetic sensors. Molecular imprinting leads to the formation of inert polymer particles with nanocavities, which can exhibit similar selectivity and specificity to target molecules as antibodies or enzymes. These sensors open up many possible applications in the field of mass-market consumer products such as food packaging sensors. One such application is the detection of histamine in spoiled fish, which causes scombroid poisoning, a common seafood poisoning.This contribution provides one possible solution for easing the use of these sensors in field applications. A screen-printed shortrange wireless MIP-based biosensor based upon passive radio frequency identification (RFID) tags was developed as a proof of principle. Histamine molecules binding to an MIP recognition layer induce a dielectric change in the sensor capacitance, resulting in a resonance frequency shift that is transmitted by inductive coupling. This wireless sensor is capable of detecting histamine concentrations as low as 50 nM at a range of a few centimeters.

Wireless Biological Electronic Sensors

“…To wirelessly transmit the sensing signals from a sensing transducer to a receiver, which is in range, passive RFIDs have been integrated with bioelectronic sensing units. Inductors are widely used to integrate with capacitors to construct inductor-capacitor (LC) or inductor-capacitor-resistor (LCR) circuits as the sensing devices [ 22 , 59 , 60 ], and the construction of the entire device structure is simple and straightforward. Dipole antennas have also been studied for wireless transmission of sensing signals [ 57 , 61 ].…”

“…Figure 1 a shows a LCR-based sensor that uses an inductor coupling to a capacitor [ 60 ], and its equivalent circuit model. An external coil is connected to an external instrument, and the instrument generates an oscillating current in the coil that further generates a magnetic field.…”

Wireless Biosensing Using Silver-Enhancement Based Self-Assembled Antennas in Passive Radio Frequency Identification (RFID) Tags

“…The principle has also been used for detecting bio-analytes and bio-markers. For instance, in [7] a molecular imprinted polymer (MIP) based passive RFID sensor was reported for detecting histamines in spoiled fish. Another example is a split-ring resonator (SRR) based RFID biosensor which was reported in [8], [9] and used for detecting prostrate-specific antigen (PSA), a prostrate cancer bio-marker.…”

Molecularly imprinted polymer–Ag2S nanoparticle composites for sensing volatile organics

“…12 The idea can be extended to other types of non-covalent interaction, which ultimately leads to biomimetic receptors. [13][14][15][16][17][18][19][20][21][22] A different approach aims at combining the properties of two or more materials, resulting e.g. in inorganic-organic composite microspheres.…”