Abstract:Psoriasis (OMIM #177900) is a common chronic disease of the skin that affects approximately 2–3% of the population. Typical lesions of psoriasis are characterised by red and scaly skin patches, usually found on the scalp, elbows and knees and often associated with severe arthritis. These lesions are caused by abnormal keratinocyte proliferation and infiltration of inflammatory cells into the dermis and epidermis. The onset of the disease is generally between 10 and 40 years of age. Type 1 begins at or before t… Show more
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