“…Such graphs arise naturally in a number of different application domains including network intrusion [33,28], semantic web [3], behavioral modeling [43,36], VLSI reverse engineering [46], link analysis [24,27,26,38], chemical compound classification [8,29,14,9], and macromolecule analysis [39]. Moreover, they can be used to effectively model the structural and relational characteristics of a variety of datasets arising in other areas such as physical sciences (e.g., chemistry, fluid dynamics, astronomy, structural mechanics, and ecosystem modeling), life sciences (e.g., genomics, proteomics, pharmacogenomics, and health informatics), and home-land defense (e.g., information assurance, network intrusion, infrastructure protection, and terrorist-threat prediction/identification).…”