Molecular evidence that the opportunistic fungal pathogen Trichosporon asahii is part of the normal fungal microbiota of the human gut based on rRNA genotyping

Cho, Otomi; Matsukura, Manami; Sugita, Takashi

doi:10.1016/j.ijid.2015.09.009

Cited by 39 publications

(26 citation statements)

References 9 publications

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“…The relative abundance of Candida in activated sludge should mainly derive from municipal wastewater. According to previous reports, Trichosporon species have been isolated from a wide range of substrates, including human hair, soil, and cheese, which should be the sources of the accumulated Trichosporon in activated sludge (Cho et al 2015;Evans and Seviour 2012). Previous reports have indicated that Trichosporon hyphae are involved in the formation of biofilms and sludge flocs and contribute greatly to the degradation of caffeine and sec-hexylbenzene in wastewater (Lakshmi and Das 2013;Nhi-Cong le et al 2016).…”

Section: Resultsmentioning

confidence: 99%

Ignored fungal community in activated sludge wastewater treatment plants: diversity and altitudinal characteristics

Niu

Xu³

et al. 2016

Environ Sci Pollut Res

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Fungi are important contributors to the various functions of activated sludge wastewater treatment plants (WWTPs); however, the diversity and geographic characteristics of fungal populations have remained vastly unexplored. Here, quantitative polymerase chain reaction and 454 pyrosequencing were combined to investigate the abundance and diversity of the activated sludge fungal communities from 18 full-scale municipal WWTPs in China. Phylogenetic taxonomy revealed that the members of the fungal communities were assigned to 7 phyla and 195 genera. Ascomycota and Basidiomycota were the most abundant phyla, dominated by Pluteus, Wickerhamiella, and Penicillium. Twenty-three fungal genera, accounting for 50.1 % of the total reads, were shared by 18 WWTPs and constituted a core fungal community. The fungal communities presented similar community diversity but different community structures across the WWTPs. Significant distance decay relationships were observed for the dissimilarity in fungal community structure and altitudinal distance between WWTPs. Additionally, the community evenness increased from 0.25 to 0.7 as the altitude increased. Dissolved oxygen and the C/N ratio were determined to be the most dominant contributors to the variation in fungal community structure via redundancy analysis. The observed data demonstrated the diverse occurrence of fungal species and gave a marked view of fungal community characteristics based on the previously unexplored fungal communities in activated sludge WWTPs.

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Section: Resultsmentioning

confidence: 99%

Ignored fungal community in activated sludge wastewater treatment plants: diversity and altitudinal characteristics

Niu

Xu³

et al. 2016

Environ Sci Pollut Res

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“…were recently reported [35–38]. A few studies suggested that GI colonization could be one of the potential sources for deep-seated yeast infections [39, 40]. …”

Section: Discussionmentioning

confidence: 99%

Diversity, in-vitro virulence traits and antifungal susceptibility pattern of gastrointestinal yeast flora of healthy poultry, Gallus gallus domesticus

et al. 2017

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BackgroundPoultry farming and consumption of poultry (Gallus gallus domesticus) meat and eggs are common gastronomical practices worldwide. Till now, a detailed understanding about the gut colonisation of Gallus gallus domesticus by yeasts and their virulence properties and drug resistance patterns in available literature remain sparse. This study was undertaken to explore this prevalent issue.ResultsA total of 103 specimens of fresh droppings of broiler chickens (commercial G domesticus) and domesticated chickens (domesticated G domesticus) were collected from the breeding sites. The isolates comprised of 29 (33%) Debaryozyma hansenii (Candida famata), 12 (13.6%) Sporothrix catenata (C. ciferrii), 10 (11.4%) C. albicans, 8 (9.1%) Diutnia catenulata (C. catenulate), 6 (6.8%) C. tropicalis, 3 (3.4%) Candida acidothermophilum (C. krusei), 2 (2.3%) C. pintolopesii, 1 (1.1%) C. parapsilosis, 9 (10.2%) Trichosporon spp. (T. moniliiforme, T. asahii), 4 (4.5%) Geotrichum candidum, 3 (3.4%) Cryptococcus macerans and 1 (1%) Cystobasidium minuta (Rhodotorula minuta). Virulence factors, measured among different yeast species, showed wide variability. Biofilm cells exhibited higher Minimum Inhibitory Concentration (MIC) values (μg/ml) than planktonic cells against all antifungal compounds tested: (fluconazole, 8–512 vs 0.031–16; amphotericin B, 0.5–64 vs 0.031–16; voriconazole 0.062–16 vs 0.062–8; caspofungin, 0.062–4 vs 0.031–1).ConclusionsThe present work extends the current understanding of in vitro virulence factors and antifungal susceptibility pattern of gastrointestinal yeast flora of G domesticus. More studies with advanced techniques are needed to quantify the risk of spread of these potential pathogens to environment and human.

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“…Trichosporon asahii is a basidiomycetous yeast that has been isolated from environmental sources as well as detected on the skin and in the gut of healthy individuals (Zhang et al ., ; Cho et al ., ). T .…”

Section: Introductionmentioning

confidence: 97%

Cell surface hydrophobicity and colony morphology ofTrichosporon asahiiclinical isolates

Ichikawa

Hirata

Takei

et al. 2016

Yeast

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Trichosporon asahii is a pathogenic basidiomycetous yeast. Individual strains of T. asahii have different colony morphologies. However, it is not clear whether cell surface phenotypes differ among the colony morphologies. Here we characterized the cell surface hydrophobicity and analysed the carbohydrate contents of the cell surface polysaccharides in T. asahii clinical isolates with various colony morphologies. Among the three distinctive colony morphologies obtained from one clinical isolate, the white-type morphology exhibited higher hydrophobicity. The hydrophobicity of heat-killed T. asahii cells was greatly reduced after periodate oxidation of the cell surface carbohydrates. Furthermore, the cell wall and extracellular polysaccharide components differed among the morphologies. Our results suggest that T. asahii cell surface hydrophobicity is affected by cell surface carbohydrate composition. Copyright © 2016 John Wiley & Sons, Ltd.

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Molecular evidence that the opportunistic fungal pathogen Trichosporon asahii is part of the normal fungal microbiota of the human gut based on rRNA genotyping

Cited by 39 publications

References 9 publications

Ignored fungal community in activated sludge wastewater treatment plants: diversity and altitudinal characteristics

Ignored fungal community in activated sludge wastewater treatment plants: diversity and altitudinal characteristics

Diversity, in-vitro virulence traits and antifungal susceptibility pattern of gastrointestinal yeast flora of healthy poultry, Gallus gallus domesticus

Cell surface hydrophobicity and colony morphology ofTrichosporon asahiiclinical isolates

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