2004
DOI: 10.1016/j.jas.2003.12.006
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Molecular evidence of tuberculosis induced hypertrophic osteopathy in a 16th-century Iroquoian dog

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Cited by 30 publications
(23 citation statements)
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“…Previous research suggests that this particular dog suffered from HPO most likely linked to a M. tuberculosis infection (Bathurst & Barta, 2004).…”
Section: Methodsmentioning
confidence: 82%
See 1 more Smart Citation
“…Previous research suggests that this particular dog suffered from HPO most likely linked to a M. tuberculosis infection (Bathurst & Barta, 2004).…”
Section: Methodsmentioning
confidence: 82%
“…Confirmation and expansion of an original macroscopic and molecular diagnosis for tuberculosis (TB) induced HPO (Bathurst & Barta, 2004) was accomplished using microscopic techniques on a 16 th -century Iroquoian canid metacarpal bone. The advanced information obtained in this study provides an avenue for discussion concerning the similarities in skeletal manifestations that humans and other mammals share in response to certain diseases.…”
Section: Introductionmentioning
confidence: 99%
“…Tuberculosis appears to be singular in this respect, in that there is a growing body of papers which report recovery of tuberculosis DNA from human and animal remains (2,11). This can in part be explained by the readily identified nature of skeletal lesions and by the extremely robust character of the mycobacterial cell wall (25).…”
Section: Discussionmentioning
confidence: 99%
“…The growth of this field of paleomicrobiology is summarized in Table 1 for ancient tuberculosis [4,5,9,10,[22][23][24][25][26][27][28][29][30][31][32][33] and in Table 2 for ancient leprosy [6,11,14,18,[34][35][36][37][38][39][40], highlighting the changes in methodology over time. Detailed information for a range of studies on ancient tuberculosis is provided in Table S1 [4,5,9,10,[22][23][24][25][26][27][28][29][30][31][32][33]36,.…”
Section: Introductionmentioning
confidence: 99%
“…Detailed information for a range of studies on ancient tuberculosis is provided in Table S1 [4,5,9,10,[22][23][24][25][26][27][28][29][30][31][32][33]36,. Similarly, studies on ancient leprosy are tabulated in Table S2 [6,[11][12][13][14]18,20,[34][35][36][37][38][39][40]53,[68][69][70][71][72][73][74][75][76].…”
Section: Introductionmentioning
confidence: 99%