Molecular epidemiology of infectious laryngotracheitis: a review

Menendez, Kimberly R.; Garcı́a, Maricarmen; Spatz, Stephen J.; Tablante, Nathaniel L.

doi:10.1080/03079457.2014.886004

Cited by 68 publications

(59 citation statements)

References 59 publications

(89 reference statements)

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“…Chicken-embryo origin vaccines (CEO) show a greater tendency to increase their virulence with bird-to-bird passage relative to those of tissue-culture origin (TCO) (Guy et al, 1991;Kotiw et al, 1995). Recent epidemiological studies indicate that the ILT outbreaks reported around the world are mainly related to the use of live attenuated vaccines (Menendez et al, 2014).…”

Section: Vaccinationmentioning

confidence: 99%

Epidemiology of Avian Infectious Laryngotracheitis with Special Focus to South America: an update

Parra

Nuñez

Ferreira

2016

Rev. Bras. Cienc. Avic.

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Section: Vaccinationmentioning

confidence: 99%

Epidemiology of Avian Infectious Laryngotracheitis with Special Focus to South America: an update

Parra

Nuñez

Ferreira

2016

Rev. Bras. Cienc. Avic.

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“…It has been speculated that incomplete en mass vaccination, particularly with CEO vaccines, results in long-term persistence of selective vaccine subpopulations (García & Riblet, 2001;García et al, 2013b). Subsequently these strains regain virulence and are responsible for outbreaks of the disease worldwide (Menendez et al, 2014). In order to obtain more stable attenuated strains of ILTV, deletion of genes related to virulence has been extensively pursued (Fuchs et al, 2007).…”

Section: Introductionmentioning

confidence: 99%

Attenuation and protection efficacy of ORF C gene-deleted recombinant of infectious laryngotracheitis virus

Garcı́a

Spatz

Cheng

et al. 2016

Journal of General Virology

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“…Among the IAPs, XIAP is the most extensively studied. 7 XIAP has been demonstrated to be powerfully anti-apoptotic by directly binding to caspases and inhibiting their activity. The loss or inhibition of XIAP results in cells that are sensitized to death receptor-induced cell death.…”

Section: Introductionmentioning

confidence: 99%

XIAP 3′-untranslated region serves as a competitor for HMGA2 by arresting endogenous let-7a-5p in human hepatocellular carcinoma

Tao

Wang

et al. 2017

Tumour Biol.

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X-linked inhibitor of apoptosis protein functions as an intrinsic regulator of apoptosis by inhibition of caspase activity and possesses a pivotal role in human cancer development and progression. A growing body of literature has demonstrated that microRNAs lead to the degradation or translational repression of messenger RNAs by binding to the non-coding region of messenger RNA at the 3′-untranslated region. Here, we revealed that the expression of HMGA2 is upregulated with X-linked inhibitor of apoptosis protein after transfection of X-linked inhibitor of apoptosis protein 3′-untranslated region in hepatocellular carcinoma cells, suggesting that X-linked inhibitor of apoptosis protein 3′-untranslated region serves as a competitor for microRNAs and prevent the co-targeted messenger RNA, HMGA2, from being suppressed. We further identified that let-7a-5p could bind to both the X-linked inhibitor of apoptosis protein 3′-untranslated region and HMGA2 3′-untranslated region. Moreover, we demonstrated that the forced expression of X-linked inhibitor of apoptosis protein 3′-untranslated region increases the oncogenicity of hepatocellular carcinoma cells in vitro. Cell functional analyses were performed to examine the association of HMGA2 status and X-linked inhibitor of apoptosis protein 3′-untranslated region. We have also measured the functional readout of let-7a-5p and HMGA2, an assay often employed to provide substantial evidence for the effects of X-linked inhibitor of apoptosis protein 3′-untranslated region on hepatocellular carcinoma cells. In general, our findings suggest that X-linked inhibitor of apoptosis protein 3′-untranslated region serves as a competitive endogenous RNA for HMGA2 to activate hepatocellular carcinoma progression by arresting endogenous let-7a-5p. Keywords X-linked inhibitor of apoptosis protein, HMGA2, 3′-untranslated region, microRNA, hepatocellular carcinoma Date

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Molecular epidemiology of infectious laryngotracheitis: a review

Cited by 68 publications

References 59 publications

Epidemiology of Avian Infectious Laryngotracheitis with Special Focus to South America: an update

Epidemiology of Avian Infectious Laryngotracheitis with Special Focus to South America: an update

Attenuation and protection efficacy of ORF C gene-deleted recombinant of infectious laryngotracheitis virus

XIAP 3′-untranslated region serves as a competitor for HMGA2 by arresting endogenous let-7a-5p in human hepatocellular carcinoma

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