Molecular epidemiology of giardiasis from a veterinary perspective

Ryan, Una; Zahedi, Alireza

doi:10.1016/bs.apar.2019.07.002

Cited by 76 publications

(69 citation statements)

References 272 publications

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“…A study in Algeria (Sahraoui et al, p. 171 in [31]) used two markers to type Giardia isolates from lambs and identified assemblage A in a minority of the isolates. Finally, a study of captive non-human primates (Koster et al, p. 179 in [31]) confirmed a high prevalence of giardiasis in these animals, with a predominance of assemblage B [38].…”

Section: Animal Epidemiologymentioning

confidence: 95%

Update on Giardia: Highlights from the seventh International Giardia and Cryptosporidium Conference

et al. 2020

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Although Giardia duodenalis is recognized as one of the leading causes of parasitic human diarrhea in the world, knowledge of the mechanisms of infection is limited, as the pathophysiological consequences of infection remain incompletely elucidated. Similarly, the reason for and consequences of the very specific genome-organization in this parasite with 2 active nuclei is only partially known. Consistent with its tradition, the 7th International Giardia and Cryptosporidium Conference (IGCC 2019) was held from June 23 to 26, 2019, at the Faculty of Medicine and Pharmacy of the University of Rouen-Normandie, France, to discuss current research perspectives in the field. This renowned event brought together an international delegation of researchers to present and debate recent advances and identify the main research themes and knowledge gaps. The program for this interdisciplinary conference included all aspects of host-parasite relationships, from basic research to applications in human and veterinary medicine, as well as the environmental issues raised by water-borne parasites and their epidemiological consequences. With regard to Giardia and giardiasis, the main areas of research for which new findings and the most impressive communications were presented and discussed included: parasite ecology and epidemiology of giardiasis, Giardia-host interactions, and cell biology of Giardia, genomes and genomic evolution. The high-quality presentations discussed at the Conference noted breakthroughs and identified new opportunities that will inspire researchers and funding agencies to stimulate future research in a “one health” approach to improve basic knowledge and clinical and public health management of zoonotic giardiasis.

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Section: Animal Epidemiologymentioning

confidence: 95%

Update on Giardia: Highlights from the seventh International Giardia and Cryptosporidium Conference

et al. 2020

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“…(32,40,41,59,60,61) The low investment in tools with discriminatory potential results that sequencing is still the most widely used methodology, although it may present divergences according to the gene target used. The whole genome sequencing (WGS) is suggested for genotyping; (10) however, the high cost and the delay in obtaining results prevent its use on a large scale, especially in developing countries, such as Brazil.…”

Section: Genotyping Strategies Of G Duodenalis In Brazilmentioning

confidence: 99%

“…(5,7) The assemblage E was considered only infecting ungulate and biungulate animals, but the human infection has been reported. (8,9,10) Yet, the affinity of these assemblages for the hosts has been constantly discussed and updated. (11) When symptomatic, the most frequent symptoms of giardiasis are consequence of acute or chronic diarrhoea, such as abdominal colic, flatulence, dehydration, nausea, vomiting and fatigue.…”

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confidence: 99%

Epidemiology of Giardia duodenalis assemblages in Brazil: there is still a long way to go

Fantinatti

Gonçalves-Pinto

Lopes-Oliveira

et al. 2020

Mem. Inst. Oswaldo Cruz

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Giardia duodenalis infection is distributed worldwide and can achieve prevalence around 60%, especially in developing countries. This protozoan is divided into eight assemblages, in which A and B have high zoonotic potential, whereas C to H are host-specific. This scenario is changing as molecular studies progress, highlighting that knowledge on host-specificity still has a long way to go. Understanding the players involved in transmission routes enables rational designs of control strategies. Considering the high prevalence of giardiasis, this review aims to gather together the data on available studies on the distribution of G. duodenalis assemblages in Brazil until September 2020.

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“…Giardiasis is the most common enteric protozoan parasitic infection worldwide, with an estimated 280 million people infected annually. The species that infects humans, Giardia duodenalis, is a species complex consisting of eight assemblages (A-H), with assemblages A and B the dominant assemblages in humans and assemblages C-H in animals, although sporadic cases of assemblages C, D, E and F have been reported in humans (Ryan and Zahedi 2019). Giardia infections can be asymptomatic or result in diarrhoea that can become chronic and has also been associated with irritable bowel syndrome, chronic fatigue and joint pain (Coffey et al 2020).…”

Section: Introductionmentioning

confidence: 99%

Wastewater-based epidemiology—surveillance and early detection of waterborne pathogens with a focus on SARS-CoV-2, Cryptosporidium and Giardia

et al. 2021

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Waterborne diseases are a major global problem, resulting in high morbidity and mortality, and massive economic costs. The ability to rapidly and reliably detect and monitor the spread of waterborne diseases is vital for early intervention and preventing more widespread disease outbreaks. Pathogens are, however, difficult to detect in water and are not practicably detectable at acceptable concentrations that need to be achieved in treated drinking water (which are of the order one per million litre). Furthermore, current clinical-based surveillance methods have many limitations such as the invasive nature of the testing and the challenges in testing large numbers of people. Wastewater-based epidemiology (WBE), which is based on the analysis of wastewater to monitor the emergence and spread of infectious disease at a population level, has received renewed attention in light of the current coronavirus disease 2019 (COVID-19) pandemic. The present review will focus on the application of WBE for the detection and surveillance of pathogens with a focus on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the waterborne protozoan parasites Cryptosporidium and Giardia. The review highlights the benefits and challenges of WBE and the future of this tool for community-wide infectious disease surveillance.

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Molecular epidemiology of giardiasis from a veterinary perspective

Cited by 76 publications

References 272 publications

Update on Giardia: Highlights from the seventh International Giardia and Cryptosporidium Conference

Update on Giardia: Highlights from the seventh International Giardia and Cryptosporidium Conference

Epidemiology of Giardia duodenalis assemblages in Brazil: there is still a long way to go

Wastewater-based epidemiology—surveillance and early detection of waterborne pathogens with a focus on SARS-CoV-2, Cryptosporidium and Giardia

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