Abstract:The effect of the protonation state
of glutamic acid on its translocation
through cyclic peptide nanotubes (CPNs) was assessed by using molecular
dynamics (MD) simulations. Anionic (GLU−), neutral zwitterionic
(GLU0), and cationic (GLU+) forms of glutamic acid were selected as
three different protonation states for an analysis of energetics and
diffusivity for acid transport across a cyclic decapeptide nanotube.
Based on the solubility-diffusion model, permeability coefficients
for the three protonation states… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.