Molecular Docking of Spearmint Phytocompounds Against Cyp21a2: Implications for Pcos Therapy
SNEHA MALAKHED
Abstract:Objectives: In this study, phytocompounds of spearmint that is known to have anti-androgenic activity are docked against a protein CYP21A2. This protein is also known as progesterone complex, one of the member cytochrome P450 enzymes; mutations in the genes encoding these proteins are causative factors of polycystic ovarian syndrome (PCOS).
Methods: The study was based on computations using different phytochemicals of spearmint docking to a target protein CYP21A2 which causes hormonal imbalance leading to PCOS… Show more
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