Molecular detection of spotted fever group rickettsiae in hard ticks, northern China

Guo, Wen‐Ping; Wang, Yihan; Lu, Qizhong; Xu, Gang; Luo, Yuhang; Ni, Xue-Bing; Zhou, En‐Min

doi:10.1111/tbed.13184

Cited by 29 publications

(36 citation statements)

References 64 publications

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“…Rickettsia species are pathogens with zoonotic characteristics that are strictly intracellular, Gram‐negative bacteria from the order Rickettsiales, comprising 30 recognized species and numerous uncharacterized sequences (Guo et al, ; Shpynov, Pozdnichenko, & Gumenuk, ).…”

Section: Introductionmentioning

confidence: 99%

Pathogenic Rickettsia in ticks of spur‐thighed tortoise ( Testudo graeca ) sold in a Qatar live animal market

Barradas

Mesquita

Lima

et al. 2019

Transbound Emerg Dis

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The dissemination of vector arthropods harbouring zoonotic pathogens through the uncontrolled transboundary trade of exotic and pet animals poses an important threat to Public Health. In the present report, we describe the introduction of pathogenic Rickettsia africae and R. aeschlimanni in ticks removed from imported tortoises in Qatar. A total of 21 ticks were collected from pet spur‐thighed tortoises (Testudo graeca) from Doha, May 2018, and studied for species identification and characterization of Rickettsia spp. Morphological and molecular analysis of ticks allowed their identification as Hyalomma aegyptium. Molecular analysis of partial ompA and gltA genes showed that Rickettsia sequences found on these ticks clustered with sequences classified as R. aeschilimanii and R. africae. Since pre‐adult stages of H. aegyptium also feed on humans, this tick species may play a role in the transmission of R. aeschilimanii and R. africae. We alert for the introduction of non‐native pets as vehicles for tick importation, known vectors for animal and human pathogenic agents. Importation of exotic species into non‐autochthonous countries deserves strict control to enforce robust surveillance and mitigate potential exotic diseases epidemics.

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Section: Introductionmentioning

confidence: 99%

Pathogenic Rickettsia in ticks of spur‐thighed tortoise ( Testudo graeca ) sold in a Qatar live animal market

Barradas

Mesquita

Lima

et al. 2019

Transbound Emerg Dis

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“…The others were given provisory species names, including Candidatus Rickettsia jingxinensis from H. longicornis (1.0%, 2/204 pools) in China [28]. The two uncultured Rickettsia species were found to be the same species by phylogenetic analysis involving several genes [29]. In a previous study, unidentified new Rickettsia spp.…”

Section: Discussionmentioning

confidence: 96%

“…In a previous study, unidentified new Rickettsia spp. in H. longicornis were Candidatus R. longicornii (16.7%, 52/311 pools) in South Korea [12] and Candidatus R. jingxinensis (32.0%, 303/947) in China [29]. Moreover, the XY118 (KU853023) isolate was obtained from a human, indicating its possible pathogenicity in humans.…”

Section: Discussionmentioning

confidence: 99%

Molecular and Phylogenetic Analysis of Tick-Borne Pathogens in Ticks Parasitizing Native Korean Goats (Capra hircus coreanae) in South Korea

2020

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Tick-borne pathogens (TBPs) are considered zoonotic re-emerging pathogens, with ticks playing important roles in their transmission and ecology. Previous studies in South Korea have examined TBPs residing in ticks; however, there is no phylogenetic information on TBPs in ticks parasitizing native Korean goat (NKG; Capra hircus coreanae). The present study assessed the prevalence, risk factors, and co-infectivity of TBPs in ticks parasitizing NKGs. In total, 107 hard ticks, including Haemaphysalis longicornis, Ixodes nipponensis, and Haemaphysalis flava, were obtained from NKGs in South Korea between 2016 and 2019. In 40 tested tick pools, genes for four TBPs, namely Coxiella-like endosymbiont (CLE, 5.0%), Candidatus Rickettsia longicornii (45.0%), Anaplasma bovis (2.5%), and Theileria luwenshuni (5.0%) were detected. Ehrlichia, Bartonella spp., and severe fever with thrombocytopenia syndrome virus were not detected. To our knowledge, this is the first study to report CLE and T. luwenshuni in H. flava ticks in South Korea. Considering the high prevalence of Candidatus R. longicornii in ticks parasitizing NKGs, there is a possibility of its transmission from ticks to animals and humans. NKG ticks might be maintenance hosts for TBPs, and we recommend evaluation of the potential public health threat posed by TBP-infected ticks.

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“…Subsequently, R. raoultii was found in 12 species belonging to 6 genera of ticks in Europe, North Africa and Asia and the tick species belonging to the genus Dermacentor have been confirmed as the major reservoir and vector of this rickettsial species [38,[45][46][47][48][49][50][51]. R. raoultii is widely distributed in Northeastern China and the Far-East/Siberia areas of Russia and ticks belonging to Dermacentor species were confirmed as the common natural hosts [49][50][51][52][53][54]. In this study, R. raoultii was detected in D. nuttalli, D. silvarum, and H. longicornis ticks in Harbin, an area of Northeastern China.…”

Section: Plos Neglected Tropical Diseasesmentioning

confidence: 99%

Distribution and molecular characterization of rickettsiae in ticks in Harbin area of Northeastern China

Shao

Zhang

et al. 2020

PLoS Negl Trop Dis

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Tick-borne rickettsioses are world-spreading infectious zoonoses. Ticks serve as reservoirs and vectors for Rickettsia and play a key role in transmission of rickettsioses. Most of the Chinese rickettsiosis patients are reported from Northeastern China but the distribution of tick and tick-borne Rickettsia species in Northeastern China remain poorly studied. In this study, a total of 1,286 ticks were captured from the seven counties of Harbin, an area in Northeastern China, and the tick-borne Rickettsia species were identified by PCR and sequencing of rrs, gltA, groEL, ompA and 17-kDa antigen-encoding genes. Of the 5 identified tick species, Haemaphysalis longicornis and Ixodes persulcatus were the predominant tick species in the livestock and vegetation, respectively. Rickettsia raoultii and "Candidatus Rickettsia tarasevichiae" were the two detectable Rickettsia species in the ticks with a 28.8% positive rate but no rickettsiae were found in ticks of Haemaphysalis concinna. R. raoultii detected in 37.6% of the Dermacentor nuttalli, Dermacentor silvarum and H. longicornis ticks while "Ca. R. tarasevichiae" was only present in 22.8% of the I. persulcatus ticks. In particular, the positive rate of both R. raoultii and "Ca. R. tarasevichiae" in ticks from the livestock (40.7%) was significantly higher than that from the vegetation (19.5%). The results indicate that the tick and tick-borne Rickettsia species are diverse in different regions of Harbin due to geographic difference and the ticks from livestock may play a more important role in transmission of rickettsioses to human.

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Molecular detection of spotted fever group rickettsiae in hard ticks, northern China

Cited by 29 publications

References 64 publications

Pathogenic Rickettsia in ticks of spur‐thighed tortoise ( Testudo graeca ) sold in a Qatar live animal market

Pathogenic Rickettsia in ticks of spur‐thighed tortoise ( Testudo graeca ) sold in a Qatar live animal market

Molecular and Phylogenetic Analysis of Tick-Borne Pathogens in Ticks Parasitizing Native Korean Goats (Capra hircus coreanae) in South Korea

Distribution and molecular characterization of rickettsiae in ticks in Harbin area of Northeastern China

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