Molecular detection of OprD and ExoA in Pseudomonas aeruginosa and antibiotics resistance

Saleh, Ruqaiya Mahmoud; Motib, Anfal Shakir

doi:10.1063/5.0103074

Cited by 1 publication

(1 citation statement)

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“…Throat swabs were taken from pediatric pharyngitis patients that suspected to isolate Streptococcus spp. from these swaps and antibiotic susceptibility tests were done for this bacterium species [12,13]. In addition, exclusion criteria was considered and was included the following patients: patients with concurrent infections other than streptococcal pharyngitis, patients with chronic diseases affecting the immune system, such as HIV/AIDS or congenital immunodeficiency, patients with incomplete medical records or missing laboratory results, and recent antibiotics within the past month.…”

Section: Methodsmentioning

confidence: 99%

Antibiotic susceptibility of Streptococcus species that cause pharyngitis in children

Ammar Amin,

Hameed Wadi,

Abed Hasan AL-Gburi

et al. 2024

DJM

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Background: Group A Streptococcus (GAS) significantly impacts global health, especially among children aged 5–14 years, causing approximately 288 million episodes of sore throat annually and resulting in around 100,000 disability-adjusted life years (DALYs) each year. GAS infections are particularly prevalent in developing countries. Objective: To assess the patterns of antibiotic resistance of Streptococcus spp. that cause pharyngitis in children. Patients and Methods: It was collected 100 pediatric patients. It was taken throat swabs for Streptococcus species culture and antibiotic sensitivity test. In addition, it was recorded the data of patient’s age and gender. Results: It was shown in this study that an average age of 4.4 ± 3.7 years for pharyngitis in children. In this study was diagnosed that Streptococcus agalactiae (24%) and Streptococcus pyogenes (18%) as the common causes Streptococcus species causes pharyngitis in children. It was noted that the differences in bacterial species according to the patient’s ages. Antibiotic sensitivity testing determined that there are high sensitivity of S. pneumoniae and S. parasanguinis to multiple antibiotics. In addition, it was showed resistance of S. pyogenes to Metronidazole and Azithromycin. Conclusion: In this study, it was found that the risk age for pharyngitis in children is four years old. Streptococcus agalactiae and Streptococcus pyogenes are the common bacterial causes for this infection. In addition, it was shown that S. pneumoniae appeared a high sensitivity to Ceftriaxone, Ciprofloxacin, and Meropenem, and S. parasanguinis was sensitive to Azithromycin, Cefixime, and Cefotaxime, and S. pyogenes showed a high sensitivity to Meropenem and Imipenem. Keywords: Pharyngitis, Streptococcus pyogenes, Children infection, antibiotic resistance.

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Section: Methodsmentioning

confidence: 99%