Molecular detection of Hepatozoon canis in dogs from Kerala

Lakshmanan, Bindu; Jose, K. Jain; George, Arun; Usha, N. P.; Devada, K.

doi:10.1007/s12639-018-0998-7

Cited by 4 publications

(2 citation statements)

References 13 publications

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“…In the surveyed dog population, a large percentage of samples (53.8%) tested positive for H. canis , indicating that this pathogen is commonly found in the Ethiopian territory. The sequences obtained from positive samples of the study area were found to be very similar to specimens isolated from the black-backed jackal ( Canis mesomelas ) in South Africa [ 72 ], from the grey wolf ( Canis lupus ) in Germany [ 73 ] and from the dog in India [ 74 ]. The presence of this piroplasm in several African countries was already documented.…”

Section: Discussionmentioning

confidence: 97%

Epidemiological Survey on Tick-Borne Pathogens with Zoonotic Potential in Dog Populations of Southern Ethiopia

et al. 2023

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Dogs are known to host several tick-borne pathogens with zoonotic potential; however, scant information is available on the epidemiology of these pathogens in low-income tropical countries and in particular in sub-Saharan Africa. With the aim of investigating a wide range of tick-borne pathogens (i.e., Rickettsia spp., Anaplasma spp., Erhlichia spp., Borrelia spp., Hepatozoon spp. and Babesia spp.), 273 blood samples were collected from dogs in selected districts of Ethiopia and analyzed by real-time and/or end-point PCR. The results of the study showed that Hepatozoon canis was the most prevalent pathogen (53.8%), followed by Anaplasma phagocythophilum (7.0%), Babesia canis rossi (3.3%), Ehrlichia canis (2.6%) and Anaplasma platys (2.2%). Furthermore, five samples tested positive for Borrelia spp., identified as Borrelia afzelii (n = 3) and Borrelia burgdorferi (n = 2), and two samples for Rickettsia spp., identified as Rickettsia conorii (n = 1) and Rickettsia monacensis (n = 1). The finding of Anaplasma phagocythophilum and different species of the genera Borrelia and Rickettsia with zoonotic potential was unexpected and alarming, and calls for further investigation on the roles of dogs and on the tick, species acting as vector in this specific context. Other pathogens (Hepatozoon canis, Babaesia canis rossi, Anaplasma platys, Ehrlichia canis) are already known to have an important impact on the dogs’ health but have minor zoonotic potential as they were rarely or never reported in humans. Dogs from rural areas were found to be at higher risk for different pathogens, probably due to the presence of other wild canids in the same environment. The findings of the present study contribute to a better knowledge of the epidemiology of tick-borne pathogens, which is relevant to human and animal health.

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Section: Discussionmentioning

confidence: 97%

Epidemiological Survey on Tick-Borne Pathogens with Zoonotic Potential in Dog Populations of Southern Ethiopia

et al. 2023

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“…Recently, in Galenbindunuwewa, H. canis has been reported with B. gibsoni infections [6]. Hepatozoon canis is a common CVBD and has been reported from several parts in India [59] and also is distributed throughout the old world. Disease-associated with the infection is usually asymptomatic, while disease, when present, may range from subclinical and chronic, especially in the absence of concurrent infections, to severe and life-threatening [60].…”

Section: Discussionmentioning

confidence: 99%

Canine Vector-Borne Diseases of Working Dogs of the Sri Lanka Air Force, Free-Roaming, and Privately-Owned Dogs

Rajakaruna

Jayathilake²,

Wijerathna

et al. 2021

Preprint

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Background Canine vector-borne diseases (CVBDs) are a significant health problem among dogs globally. The veterinary records show that the military working dogs of Sri Lanka die early at an average age of six years and CVBDs have been listed as one of the speculated causes. This study examined CVBDs in the working dogs of the Sri Lanka Air Force (SLAF) together with free-roaming and privately-owned dogs living close to the SLAF establishments and country-wide. Methods Blood samples were collected from the cephalic vein for a three year period, from July 2016 to July 2019. Giemsa stained thin blood smears were observed under light microscopy. Results A total of 668 dogs were sampled, of which 169 were infected (25.3%) with hemoparasites. The prevalence of infections among the SLAF working dogs (22.5%), free-roaming (26.3%), or privately-owned (26.2%) dogs did not differ significantly (Chi-square test, p > 0.05). A large number of infected dogs were asymptomatic (57.4%), which was significantly higher in free-roaming dogs (96.3%) compared to the SLAF (41.1%) and privately-owned dogs (38.2%; p < 0.0001) but not between SLAF dogs and privately-owned dogs (χ2 = 0.005, p > 0.938). Seven hemoparasites were identified: Babesia gibsoni, B. canis, Ehrlichia canis, Anaplasma platys, Leishmania sp., Hepatozoon canis, and microfilariae. The most common infection was B. gibsoni (13.8%) followed by E. canis (9.9%) and A. platys (4.3%). There was no difference in the prevalence of B. gibsoni in the three categories of dogs (χ2 = 2.61, p = 0.10). Leishmania and H. canis were always presented as single infections, while microfilaria as mixed infections. Conclusions Even though the SLAF dogs are thoroughly quarantined before introducing them to the military units, the infection prevalence was similar compared to other dog categories. They have likely acquired the infections through ticks and other arthropod vectors. This is the first comprehensive and comparative island-wide study of dog CVBDs of Sri Lanka, especially the military dogs at the SLAF. It highlights that most infected dogs, especially the free-roaming ones, did not show clinical signs. Although it is speculated that they may act as reservoirs of infection, asymptomatic dogs' ability to spread these CVBDS should be investigated.

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Pathogenic effects of Hepatozoon canis (Apicomplexa: Hepatozoidae) on pet dogs (Canis familiaris) with amplification of immunogenetic biomarkers

Khalifa,

Attia

2023

Comp Clin Pathol

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Molecular detection of Hepatozoon canis in dogs from Kerala

Cited by 4 publications

References 13 publications

Epidemiological Survey on Tick-Borne Pathogens with Zoonotic Potential in Dog Populations of Southern Ethiopia

Epidemiological Survey on Tick-Borne Pathogens with Zoonotic Potential in Dog Populations of Southern Ethiopia

Canine Vector-Borne Diseases of Working Dogs of the Sri Lanka Air Force, Free-Roaming, and Privately-Owned Dogs

Pathogenic effects of Hepatozoon canis (Apicomplexa: Hepatozoidae) on pet dogs (Canis familiaris) with amplification of immunogenetic biomarkers

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