Molecular detection of Helicobacter pylori based on the presence of cagA and vacA virulence genes in dental plaque from patients with periodontitis

Flores-Treviño, Carlos Eduardo; Urrutia-Baca, Víctor Hugo; Gómez-Flores, Ricardo; Garza-Ramos, Myriam Angélica De La; Sánchez-Chaparro, María Marisela; Garza‐Elizondo, Mario Alberto

doi:10.1016/j.jds.2019.01.010

Cited by 31 publications

(22 citation statements)

References 33 publications

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“…The ability of H. pylori to produce H 2 S and CH 3 SH is strain-specific [ 36 ]. H. pylori has been detected in oral specimens [ 6 , 7 , 37 ], and its prevalence was associated with the progression of periodontitis. There is disagreement as to whether H. pylori is present in the oral cavity.…”

Section: Discussionmentioning

confidence: 99%

Effects of eradication of Helicobacter pylori on oral malodor and the oral environment: a single-center observational study

et al. 2020

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Objective: Although a relationship between Helicobacter pylori and oral malodor has been suggested, it remains to be confirmed. One reason for this is that many studies assess oral malodor subjectively. Another reason for the uncertainty is that the reduction in oral malodor may be due to the effect of antibiotics on the oral microbiota. In this study, changes in oral malodor along with the eradication treatment of H. pylori were investigated by organoleptic test and gas chromatography. In addition, the salivary bacterial composition and clinical parameters were analyzed. Results: The organoleptic test score, hydrogen sulfide and dimethyl sulfide concentrations, and all clinical parameters except for tongue-coating score were significantly decreased at 1 week compared with baseline. Although antibiotic treatment also altered the overall composition of the salivary bacterial population, it had recovered at 7 weeks. On the date that H. pylori was determined to have been eradicated from all of the subjects (7 weeks after treatment), only the organoleptic test score was significantly lower compared with baseline. The hydrogen sulfide and dimethyl sulfide concentrations were non-significantly lower than those at baseline.

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Section: Discussionmentioning

confidence: 99%

Effects of eradication of Helicobacter pylori on oral malodor and the oral environment: a single-center observational study

et al. 2020

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show abstract

“…The ability of H. pylori to produce H 2 S and CH 3 SH is strain-speci c [36]. H. pylori has been detected in oral specimens [6,7,37], and its prevalence was associated with the progression of periodontitis. There is disagreement as to whether H. pylori is present in the oral cavity.…”

Section: Discussionmentioning

confidence: 99%

Effects of eradication of Helicobacter pylori on oral malodor and the oral environment: a single-center observational study

Suzuki

Beppu²,

Yoneda

et al. 2020

Preprint

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Objective: Although a relationship between Helicobacter pylori and oral malodor has been suggested, it remains to be confirmed. One reason for this is that many studies assess oral malodor subjectively. Another reason for the uncertainty is that the reduction in oral malodor may be due to the effect of antibiotics on the oral microbiota. In this study, changes in oral malodor and the eradication treatment of H. pylori were investigated by organoleptic test and gas chromatography. In addition, the salivary bacterial composition and clinical parameters were analyzed.Results: The organoleptic test score, hydrogen sulfide and dimethyl sulfide concentrations, and all clinical parameters except for tongue-coating score were significantly decreased at 1 week compared with baseline. Although antibiotic treatment also altered the overall composition of the salivary bacterial population, it had recovered at 7 weeks. On the date that H. pylori was determined to have been eradicated from all of the subjects (7 weeks after treatment), only the organoleptic test score was significantly lower compared with baseline. The hydrogen sulfide and dimethyl sulfide concentrations were non-significantly lower than those at baseline.

show abstract

“…The ability of H. pylori to produce H 2 S and CH 3 SH is strain-specific [31]. H. pylori has been detected in oral specimens [6,7,32], and its prevalence was associated with the progression of periodontitis.…”

Section: Discussionmentioning

confidence: 99%

Effects of eradication of Helicobacter pylori on oral malodor and the oral environment: a single-center observational study

Suzuki

Beppu²,

Yoneda

et al. 2020

Preprint

View full text Add to dashboard Cite

Objective: Although a relationship between Helicobacter pylori and oral malodor has been suggested, it remains to be confirmed. One reason for this is that many studies assess oral malodor subjectively. Another reason for the uncertainty is that the reduction in oral malodor may be due to the effect of antibiotics on the oral microbiota. In this study, changes in oral malodor after eradication of H. pylori were investigated by organoleptic test and gas chromatography. In addition, the salivary bacterial composition and clinical parameters were analyzed.Results: The organoleptic test score, hydrogen sulfide and dimethyl sulfide concentrations, and all clinical parameters except for tongue-coating score were significantly decreased at 1 week compared with baseline. On the date that H. pylori was determined to have been eradicated from all of the subjects (7 weeks after treatment), only the organoleptic test score was significantly lower compared with baseline. Although the overall composition of the salivary bacterial populations was altered by antibiotic treatment, they had recovered at 7 weeks. Therefore, it is possible that the levels of odorous components other than volatile sulfur compounds related to oral malodor were decreased by H. pylori eradication.

show abstract

Molecular detection of Helicobacter pylori based on the presence of cagA and vacA virulence genes in dental plaque from patients with periodontitis

Cited by 31 publications

References 33 publications

Effects of eradication of Helicobacter pylori on oral malodor and the oral environment: a single-center observational study

Effects of eradication of Helicobacter pylori on oral malodor and the oral environment: a single-center observational study

Effects of eradication of Helicobacter pylori on oral malodor and the oral environment: a single-center observational study

Effects of eradication of Helicobacter pylori on oral malodor and the oral environment: a single-center observational study

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