Charge transport across the peptide chains is one of the vital processes in the biological systems, so understanding their charge transport properties is an indispensable prerequisite to explain the complex biochemical phenomenon. Here, we review the charge transport mechanism, the influence of the special groups and the experimental conditions on the charge transport through the peptide backbone by employing the single-molecule electrical measurements. Besides, we further review the recent progresses in charge transport properties of supramolecular interaction among the adjacent peptide chains. Finally, we discuss some experimental and theoretical contradictions existing in the charge transport through peptides and provide new inspiration for the future development of the bioelectronics at the single-molecule scale.Haining Zheng (left) received her BEng Degree from Qingdao University of Science and Technology in 2017. She is currently pursuing her master degree under the supervision of Prof. Wenjing Hong in Xiamen University. Her research interests include the charge transport through peptidesupramolecular interaction network and quantum interference effects of perovskite quantum dots in single-molecule scale.Feng Jiang (middle) received his BEng Degree from Qingdao University of Science and Technology in 2017. He is currently a master student under the supervision of Prof. Wenjing Hong at Xiamen University, where he is interested in the quantum interference effects in singlemolecule electronics.Prof. Wenjing Hong has been a full professor in State Key Laboratory of Physical Chemistry of Solid Surfaces and College of Chemistry and Chemical Engineering in Xiamen University. He obtained a Ph.D. degree in 2013 from the University of Bern, Switzerland under supervision of Prof. Thomas Wandlowski. His current research is mainly focused on single-molecule electronics, the applications of artificial intelligence for chemistry and chemical engineering.