Abstract. Two interstellar lines, 110 → 111 of formaldehyde at 4.831 GHz, and 220 → 211 of cyclopropenylidene at 21.590 GHz, have so far been observed in absorption against the cosmic 2.7 K background. Observation of an interstellar line in absorption against the cosmic 2.7 K background is an unusual phenomenon, and can only be possible under rather peculiar conditions developed in the molecule, generating the line. We predict that two more lines, 330 → 321 at 27.100 GHz, and 331 → 322 at 59.550 GHz of cyclopropenylidene, and three lines, 220 → 211 at 15.600 GHz, 330 → 321 at 23.100 GHz, and 331 → 322 at 39.700 GHz of ethylene oxide, may show absorption against the cosmic 2.7 K background. We speculate that such peculiar conditions are characteristic for b-type asymmetrical top molecules. -The observation of these lines may be used to place upper bounds to the density in the absorbing region.