“…IL-8 was first characterised within the lamprey [40], a fish that belongs to the most primitive vertebrate group, the agnathans. More recently, it has been discovered in the cartilaginous banded dogfish [41] and silver chimaera [42] as well as a number of teleosts [27,[43][44][45]. Until recently, all known fish IL-8 sequences lacked the ELR motif typical of mammalian IL-8 [41,42,44], however, both the haddock [27] and cod IL-8 (CAD59734) sequences have now been shown to possess this motif.…”