Molecular classification of small cell lung cancer subtypes: Characteristics, prognostic factors, and clinical translation
Hanfei Guo,
Wenqian Li,
Ye Guo
et al.
Abstract:Small cell lung cancer (SCLC) is a highly malignant tumor with a very poor prognosis; therefore, more effective treatments are urgently needed for patients afflicted with the disease. In recent years, emerging molecular classifications based on key transcription factors of SCLC have provided more information on the tumor pathophysiology, metastasis, immune microenvironment, and acquired therapeutic resistance and reflected the intertumoral heterogeneity of the various SCLC phenotypes. Additionally, advances in… Show more
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