Molecular characterization of α,β-poly[( N -hydroxyethyl)- dl –aspartamide] by light scattering and viscometry studies

Synthesis, characterisation and properties of α,β-poly(N-2-hydroxyethyl)-dl-aspartamide-graft-maleic anhydride precursors and their stimuli-responsive hydrogels

“…the dose at which the first appearance of insoluble polymer fraction is observed [33,34], although, as already pointed out, chemical crosslinks may also form in their absence. Chain scission is always a concurrent reaction to crosslinking, leading to the formation of lower molecular weight polymer chain segments.…”

“…Synthesis and characterisation of PHEA backbone were performed accordingly to well established procedures [32,33]. The batch used for the subsequent functionalisation with maleic anhydride had a weight-average molecular weight Mw = 50,000 ± 2500 Da and polydispersity index of 1.8 as determined by light scattering measurements, using a Dawn DSP-F Laser Spectra Physics Spectrometer [34].…”

Graft polymerization of p-dioxanone onto polyhydroxyethylaspartamide through ring-opening polymerization using organometallic and enzyme catalysts

“…Then the PSI was opened up by reacting with ethanolamine in dimethyl formamide to obtain α,β-Poly(N-2-hydroxyethyl)-DL-aspartamide (PHEA), which was used for grafting of p-dioxanone by ROP using both organometallic and enzyme catalysts. The PHEA is a totally biodegradable polymer and its potential applications in biological and pharmaceutical area have been explored recently [36,37]. The introduction of aliphatic polyester onto PHEA by graft polymerization would lead to the controlled degradability and physical properties.…”

A direct surface modification of iron oxide nanoparticles with various poly(amino acid)s for use as magnetic resonance probes

“…Poly(a-amino acid)s have many attractive properties such as absence of toxicity, antigenicity, and immunogenicity [37]. In particular, carboxylic group of PAsp can attach the small molecules such as drug and targeting moiety.…”