Molecular characterization of typing and subtyping of Staphylococcal cassette chromosome SCCmec types I to V in methicillin-resistant Staphylococcus aureus from clinical isolates from COVID-19 patients
Vivekanand Jadhav,
Meenakshi Bhakare,
Arundhuti Paul
et al.
Abstract:Background and Objectives: Methicillin resistance is acquired by the bacterium due to mecA gene which codes for pen- icillin-binding protein (PBP2a) having low affinity for β-lactam antibiotics. mecA gene is located on a mobile genetic el- ement called staphylococcal cassette chromosome mec (SCCmec). SCCmec genomic island comprises two site-specific recombinase genes namely ccrA and ccrB [cassette chromosome recombinase] accountable for mobility. Currently, SCCmec elements are classified into types I, II, III,… Show more
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