2020
DOI: 10.21203/rs.3.rs-30646/v3
|View full text |Cite
Preprint
|
Sign up to set email alerts
|

Molecular characterization of Plasmodium falciparum DNA-3-methyladenine glycosylase

Abstract: Background The emergence of artemisinin-resistant malaria parasites highlights the need for novel drugs and their targets. Alkylation of purine bases can hinder DNA replication and if unresolved would eventually result in cell death. DNA-3-methyladenine glycosylase (MAG) is responsible for the repair of those alkylated bases. Plasmodium falciparum (Pf)MAG was characterized for its potential for development as an anti-malarial candidate.Methods Native PfMAG from crude extract of chloroquine- and pyrimethamine-… Show more

Help me understand this report
View published versions

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Publication Types

Select...

Relationship

0
0

Authors

Journals

citations
Cited by 0 publications
references
References 45 publications
(47 reference statements)
0
0
0
Order By: Relevance

No citations

Set email alert for when this publication receives citations?